Prevalence and risk factors of wheeze and eczema in 1-year-old children: the Butajira birth cohort, Ethiopia

Summary Background The rising global prevalence of asthma and other allergic conditions has been linked to potential aetiological factors influencing the developing immune system. Objective To investigate the prevalence and associated risk factors for wheeze and eczema in 1‐year‐old children in a bi...

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Bibliographic Details
Published in:Clinical and experimental allergy 2010-04, Vol.40 (4), p.619-626
Main Authors: Belyhun, Y., Amberbir, A., Medhin, G., Erko, B., Hanlon, C., Venn, A., Britton, J., Davey, G.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Allergic diseases
Allergies
allergy
Biological and medical sciences
Chronic obstructive pulmonary disease, asthma
Cohort Studies
Eczema
Eczema - epidemiology
Eczema - etiology
Ethiopia
Ethiopia - epidemiology
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
helminth
Humans
Hypersensitivity - complications
Hypersensitivity - epidemiology
Hypersensitivity - physiopathology
Immunopathology
Infant
infants
Interviews as Topic
Male
Medical sciences
paracetamol
Pneumology
Prevalence
Respiratory Sounds - etiology
Respiratory Tract Infections - complications
Respiratory Tract Infections - epidemiology
Risk Factors
Rural Population
Skin allergic diseases. Stinging insect allergies
Surveys and Questionnaires
Young Adult
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Summary:Summary Background The rising global prevalence of asthma and other allergic conditions has been linked to potential aetiological factors influencing the developing immune system. Objective To investigate the prevalence and associated risk factors for wheeze and eczema in 1‐year‐old children in a birth cohort from Butajira, Ethiopia. Methods In 2005/6, a population‐based cohort of 1065 pregnant women was established. At 1 year of age, data on wheeze and eczema in the children were collected from the mother via an interview‐administered questionnaire, along with numerous demographic and lifestyle factors. A stool sample was also obtained from the child for geohelminth analysis. Results The prevalence of wheeze was 11.5% (103/899) and eczema 8.6% (77/899). Independent predictors of wheeze were maternal allergic history [adjusted OR (AOR)=3.00, 95% CI 1.23–7.36], paternal allergic history (AOR=2.59, 95% CI 1.08–6.25), increasing household size (P for trend=0.023; AOR=3.54, 95% CI 1.31–9.56 for 7+ vs. 1–3 individuals) and paracetamol use by the child (overall P
ISSN:0954-7894
1365-2222
DOI:10.1111/j.1365-2222.2010.03479.x