Course and outcome of childhood epilepsy: A 15‐year follow‐up of the Dutch Study of Epilepsy in Childhood

Summary Purpose:  To study the course and outcome of childhood‐onset epilepsy during 15‐year follow‐up (FU). Methods:  We extended FU in 413 of 494 children with new‐onset epilepsy recruited in a previously described prospective hospital‐based study by questionnaire. Results:  Mean FU was 14.8 years...

Full description

Saved in:
Bibliographic Details
Published in:Epilepsia (Copenhagen) 2010-07, Vol.51 (7), p.1189-1197
Main Authors: Geerts, Ada, Arts, Willem F., Stroink, Hans, Peeters, Els, Brouwer, Oebele, Peters, Boudewijn, Laan, Laura, Van Donselaar, Cees
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Anticonvulsants. Antiepileptics. Antiparkinson agents
Biological and medical sciences
Child
Child, Preschool
Children
Cohort Studies
Course
Epilepsy
Epilepsy - diagnosis
Epilepsy - epidemiology
Epilepsy - therapy
Female
Follow-Up Studies
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Humans
Infant
Infant, Newborn
Male
Medical sciences
Mortality
Nervous system (semeiology, syndromes)
Netherlands - epidemiology
Neurology
Neuropharmacology
Outcome
Pharmacology. Drug treatments
Treatment Outcome
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Purpose:  To study the course and outcome of childhood‐onset epilepsy during 15‐year follow‐up (FU). Methods:  We extended FU in 413 of 494 children with new‐onset epilepsy recruited in a previously described prospective hospital‐based study by questionnaire. Results:  Mean FU was 14.8 years (range 11.6–17.5 years). Five‐year terminal remission (TR) was reached by 71% of the cohort. Course during FU was favorable in 50%, improving in 29%, and poor or deteriorating in 16%. Mean duration of seizure activity was 6.0 years (range 0–21.5 years), strongly depending on etiology and epilepsy type. Duration was
ISSN:0013-9580
1528-1167
DOI:10.1111/j.1528-1167.2010.02546.x