Excitation wave front transients: a computer simulation study

The propagation of excitation waves in narrow pathways of 2-D excitable media through regions of impermeable and decreased excitability is investigated as a model of cardiac reentrant arrhythmias. Transient phenomena in wave front formation are studied at the entrance and exits of these pathways. Co...

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Bibliographic Details
Main Authors: Kogan, Boris Y, Karplus, Walter J, Billett, Brian S, Karpoukhin, Mikhail G
Format: Conference Proceeding
Language:English
Online Access:Get full text
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Summary:The propagation of excitation waves in narrow pathways of 2-D excitable media through regions of impermeable and decreased excitability is investigated as a model of cardiac reentrant arrhythmias. Transient phenomena in wave front formation are studied at the entrance and exits of these pathways. Computer simulations uncovered these phenomena for paths with two geometric configurations two types of borders and two types of viable tissue. We show that under certain conditions these transients can lead to the slow-down of propagation and unidirectional block.