Alveolar soft part sarcoma: A report of two cases with some histochemical and ultrastructural observations

In a survey of all malignant soft tissue tumors in the extremities and limb girdles in Finland between 1960 and 1969, only one alveolar soft part sarcoma was found among 246 tumors (0.4%). Another alveolar soft part sarcoma, diagnosed in 1976, was more thoroughly studied. There was evidence that the...

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Bibliographic Details
Published in:Cancer 1979-05, Vol.43 (5), p.1672-1677
Main Authors: Ekfors, T. O., Kalimo, H., Rantakokko, V., Latvala, M., Parvinen, M.
Format: Article
Language:English
Subjects:
Adult
Catecholamines - analysis
Cytoplasmic Granules - ultrastructure
Female
Humans
Lung Neoplasms
Male
Neoplasm Metastasis
Sarcoma - analysis
Sarcoma - ultrastructure
Soft Tissue Neoplasms - analysis
Soft Tissue Neoplasms - ultrastructure
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Summary:In a survey of all malignant soft tissue tumors in the extremities and limb girdles in Finland between 1960 and 1969, only one alveolar soft part sarcoma was found among 246 tumors (0.4%). Another alveolar soft part sarcoma, diagnosed in 1976, was more thoroughly studied. There was evidence that the characteristic crystals of alveolar soft part sarcoma are formed from the dense granules. Both were PASM‐positive at ultrastructural level. No monoamines were detected in the cells by formaldehyde‐induced fluorescence. This is a further fact to nullify the theory of the paraganglionic origin of alveolar soft part sarcoma, but the question of the histogenesis of the tumor still remains open.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197905)43:5<1672::AID-CNCR2820430517>3.0.CO;2-7