Three New Polyyne (=Polyacetylene) Glucosides from the Edible Roots of Codonopsis cordifolioidea

Three new linear C14 polyyne (=polyacetylene) glucosides, cordifolioidynes A–C (1–3), together with two known polyynes, lobetyol (4) and lobetyolin (5), and five known phenylpropanoids, i.e., sinapinaldehyde (6), coniferaldehyde (7), coniferoside (8), sachaliside (9), and isoconiferin (10), were iso...

Full description

Saved in:
Bibliographic Details
Published in:Helvetica chimica acta 2008-01, Vol.91 (1), p.90-96
Main Authors: Mei, Ren-Qiang, Lu, Qing, Hu, Yan-Fen, Liu, Hai-Yang, Bao, Fu-Kai, Zhang, Yu, Cheng, Yong-Xian
Format: Article
Language:English
Subjects:
Codonopsis cordifolioidea
Cordifolioidynes A - C
Glucosides
Polyacetylene glucosides
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Three new linear C14 polyyne (=polyacetylene) glucosides, cordifolioidynes A–C (1–3), together with two known polyynes, lobetyol (4) and lobetyolin (5), and five known phenylpropanoids, i.e., sinapinaldehyde (6), coniferaldehyde (7), coniferoside (8), sachaliside (9), and isoconiferin (10), were isolated from the roots of Codonopsis cordifolioidea. The structures of 1–3 were established from spectral evidences and by characterization of their hydrolysis products. Acid hydrolysis of 1 afforded the aglycone 1a, while hydrolysis of 2 and 3 gave the cyclization products 2a and 3a, respectively. Compounds 4–10 were isolated from this plant for the first time. The antibacterial activity of compounds 1–5 were assessed against eight microbial strains by the agar dilution method, none of them exhibited antibacterial effects at concentrations up to 100 μg/ml.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200890018