Serum eye drops, amniotic membrane and limbal epithelial stem cells—tools in the treatment of ocular surface disease

The advent of serum eye drops, amniotic membrane and limbal stem cell grafts, have transformed the treatment of diseases which result in ocular surface failure. This article provides an overview of ocular surface anatomy and failure, and how the use of serum eye drops, amniotic membrane and limbal e...

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Bibliographic Details
Published in:Cell and tissue banking 2010-02, Vol.11 (1), p.13-27
Main Authors: Rauz, Saaeha, Saw, Valerie P.
Format: Article
Language:English
Subjects:
Amnion - transplantation
Anatomy & physiology
Biological Dressings
Biomedical and Life Sciences
Biomedicine
Body fluids
Cell Biology
Corneal Diseases - diagnosis
Corneal Diseases - therapy
Epithelium, Corneal - transplantation
Eye diseases
Eye Injuries - therapy
Humans
Life Sciences
Membranes
Ophthalmic Solutions - therapeutic use
Serum
Stem cells
Transplant Surgery
Transplants & implants
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Summary:The advent of serum eye drops, amniotic membrane and limbal stem cell grafts, have transformed the treatment of diseases which result in ocular surface failure. This article provides an overview of ocular surface anatomy and failure, and how the use of serum eye drops, amniotic membrane and limbal epithelial stem cell transplantation has influenced ophthalmological practice both historically and in recent years. This review focuses on the rationale for the use of these emerging tools, how they are prepared, clinical applications, limitations, and speculates on future directions.
ISSN:1389-9333
1573-6814
DOI:10.1007/s10561-009-9128-1