Suspected ivermectin toxicosis in a miniature mule foal causing blindness

A 9‐week‐old miniature mule foal presented to the Veterinary Medical Teaching Hospital for acute blindness, ataxia, and depression following an overdose of an over‐the‐counter ivermectin‐based de‐worming medication. Ophthalmic examination and electrodiagnostic evaluation eliminated outer retinal abn...

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Bibliographic Details
Published in:Veterinary ophthalmology 2006-01, Vol.9 (1), p.29-32
Main Authors: Plummer, Caryn E., Kallberg, Maria E., Ollivier, Franck J., Brooks, Dennis E., Gelatt, Kirk N.
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
Antiparasitic Agents - poisoning
Antiparasitic Agents - therapeutic use
ataxia
blindness
Blindness - chemically induced
Blindness - therapy
Blindness - veterinary
Drug Overdose - veterinary
Electroretinography - veterinary
Equidae
ERG
ivermectin
Ivermectin - poisoning
Ivermectin - therapeutic use
Male
mule
toxicosis
Treatment Outcome
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Summary:A 9‐week‐old miniature mule foal presented to the Veterinary Medical Teaching Hospital for acute blindness, ataxia, and depression following an overdose of an over‐the‐counter ivermectin‐based de‐worming medication. Ophthalmic examination and electrodiagnostic evaluation eliminated outer retinal abnormalities as the primary cause of the bilateral blindness, implicating instead a central neurologic effect of the drug. With symptomatic and supportive care, the foal recovered fully and regained its vision.
ISSN:1463-5216
1463-5224
DOI:10.1111/j.1463-5224.2005.00431.x