Optimizing Surgical Care: A Contemporary Assessment of Temperature, Oxygen, and Glucose

Factors such as temperature, oxygen, and glucose have recently been implicated in the development of surgical sepsis by either promoting or attenuating protective components of the innate immune response. Reducing infective sequelae and the improvement of the quality of care of surgical patients is...

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Bibliographic Details
Published in:The American surgeon 2010-06, Vol.76 (6), p.571-577
Main Authors: DICKINSON, Ashley, QADAN, Motaz, POLK, Hiram C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood Glucose - analysis
Body Temperature - immunology
Critical Illness
Fever - immunology
General aspects
Humans
Hypothermia - immunology
Immunity, Innate - physiology
Intraoperative Period
Medical sciences
Monocytes - immunology
Postoperative Care
Sepsis - immunology
Surgical Wound Infection - immunology
Tumor Necrosis Factor-alpha - blood
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Summary:Factors such as temperature, oxygen, and glucose have recently been implicated in the development of surgical sepsis by either promoting or attenuating protective components of the innate immune response. Reducing infective sequelae and the improvement of the quality of care of surgical patients is a top practice priority today. These factors and their associated effects are discussed through the examination of recent clinical and scientific studies to provide an up-to-date evidence-based review.
ISSN:0003-1348
1555-9823