Solubility and dissolution kinetics of calcium oxalate renal calculi in solutions containing l-arginine: In-vitro experiments

The kinetics of dissolution of calcium oxalate (CaOX) calculi in physiological solutions containing l-arginine at different concentrations were studied using the change in the Archimedean weight of samples immersed in the solution. It was faound that arginine, which is a normal constituent of human...

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Bibliographic Details
Published in:Journal of crystal growth 2010-06, Vol.312 (12), p.1940-1944
Main Author: Atanassova, S.
Format: Article
Language:English
Subjects:
A1. Solubility
A1. Supersaturated solutions
B1. Acids
B1. Calcium compounds
Condensed matter: structure, mechanical and thermal properties
Equations of state, phase equilibria, and phase transitions
Exact sciences and technology
Physics
Solubility, segregation, and mixing
phase separation
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Summary:The kinetics of dissolution of calcium oxalate (CaOX) calculi in physiological solutions containing l-arginine at different concentrations were studied using the change in the Archimedean weight of samples immersed in the solution. It was faound that arginine, which is a normal constituent of human urine, acts at increased concentrations as a dissolving agent with respect to CaOX calculi. The possible effect of l-arginine as a natural regulator of CaOX supersaturation and crystalization in human urine is also disscused.
ISSN:0022-0248
1873-5002
DOI:10.1016/j.jcrysgro.2010.02.032