2-and 4-phenylethynylpyrenes, novel fluorescent labels for DNA

It was shown by the example of 1-, 2-, and 4-phenylethynylpyrene 2′- arabino -carbamate derivatives of uridine that the position of pyrene substitution substantially affects the spectral and photophysical properties of the fluorophore and its ability to interact with the nucleobase.

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Bibliographic Details
Published in:Russian journal of bioorganic chemistry 2008-07, Vol.34 (4), p.510-512
Main Authors: Astakhova, I. V., Korshun, V. A.
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Letters to the Editor
Life Sciences
Organic Chemistry
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Description
Summary:It was shown by the example of 1-, 2-, and 4-phenylethynylpyrene 2′- arabino -carbamate derivatives of uridine that the position of pyrene substitution substantially affects the spectral and photophysical properties of the fluorophore and its ability to interact with the nucleobase.
ISSN:1068-1620
1608-330X
DOI:10.1134/S1068162008040171