Successful Risperidone Rechallenge after Blepharospasm in a Patient with Schizophrenia: 24-Month Follow-Up

We report the case of a 44-year-old female patient with paranoid schizophrenia, who developed blepharospasm on risperidone treatment, but who was successfully rechallenged by risperidone without recurrence of blepharospasm. Possible mechanisms of action and implications for clinical care are discuss...

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Bibliographic Details
Published in:Journal of psychopharmacology (Oxford) 2003-12, Vol.17 (4), p.453-454
Main Authors: Gulati, Sanjiv, Singh, Ashok N., Libretto, Sue E.
Format: Article
Language:English
Subjects:
Adult
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
Biological and medical sciences
Blepharospasm - chemically induced
Case studies
Drug Administration Schedule
Drug therapy
Drug toxicity and drugs side effects treatment
Eyes & eyesight
Female
Humans
Medical sciences
Pharmacology. Drug treatments
Risperidone - adverse effects
Risperidone - therapeutic use
Schizophrenia
Schizophrenia - drug therapy
Side effects
Toxicity: eye
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Summary:We report the case of a 44-year-old female patient with paranoid schizophrenia, who developed blepharospasm on risperidone treatment, but who was successfully rechallenged by risperidone without recurrence of blepharospasm. Possible mechanisms of action and implications for clinical care are discussed.
ISSN:0269-8811
1461-7285
DOI:10.1177/0269881103174002