Systolic acquisition of coronary dual-source computed tomography angiography: feasibility in an unselected patient population

Objective To determine the practicability and potential dose saving of an imaging algorithm incorporating a pulsing scheme applying systolic data acquisition at heart rates >75 beats per minute (bpm). Methods Patients clinically referred for coronary computed tomography angiography (CTA) underwen...

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Bibliographic Details
Published in:European radiology 2010-06, Vol.20 (6), p.1331-1336
Main Authors: Bamberg, Fabian, Sommer, Wieland H., Schenzle, Jan C., Becker, Christoph R., Nikolaou, Konstantin, Reiser, Maximilian F., Johnson, Thorsten R. C.
Format: Article
Language:English
Subjects:
Algorithms
Cardiac
Coronary Angiography - methods
Coronary Artery Disease - diagnostic imaging
Diagnostic Radiology
Feasibility Studies
Female
Humans
Imaging
Internal Medicine
Interventional Radiology
Male
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Radiographic Image Enhancement - methods
Radiographic Image Interpretation, Computer-Assisted - methods
Radiography, Dual-Energy Scanned Projection - methods
Radiology
Reproducibility of Results
Sensitivity and Specificity
Systole
Tomography, X-Ray Computed - methods
Ultrasound
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Summary:Objective To determine the practicability and potential dose saving of an imaging algorithm incorporating a pulsing scheme applying systolic data acquisition at heart rates >75 beats per minute (bpm). Methods Patients clinically referred for coronary computed tomography angiography (CTA) underwent cardiac CTA using either a diastolic pulsing window (30–70%) or a narrow systolic pulsing window (150 ms at 300 ms). Independent investigators retrospectively determined image quality (1, excellent, to 5, unreadable) and derived effective radiation exposure. Results Among all 101 subjects (62 ± 2 years, 59% male) the predicted decrease in the best reconstruction interval for diastolic phases was 12 ms per 1 bpm [95% confidence interval (CI): -13.5 to -11.2] and -1.9 ms for systolic phases (95% CI: -3.2 to -0.62, p  = 0.004), independent of age, gender and body mass index (BMI). The systolic pulsing strategy in 47 subjects (23 subjects >75 bpm) resulted in significantly lower radiation exposure (4.97 ± 2.3 vs 9.38 ± 5.5 mSv, p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-009-1680-3