Elevated Serum IL-8 Levels in Ataxia Telangiectasia

Serum interleukin (IL)-8 levels were measured in 50 patients with ataxia telangiectasia (A-T) and 22 without A-T. In a cross-sectional study, the geometric mean of IL-8 level was significantly higher in the patients with A-T ( P

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Bibliographic Details
Published in:The Journal of pediatrics 2010-04, Vol.156 (4), p.682-684.e1
Main Authors: McGrath-Morrow, Sharon A., MD, Collaco, J. Michael, MD, Crawford, Thomas O., MD, Carson, Kathryn A., ScM, Lefton-Greif, Maureen A., PhD, Zeitlin, Pamela, MD, PhD, Lederman, Howard M., MD, PhD
Format: Article
Language:English
Subjects:
Adolescent
Adult
alpha-Fetoproteins - metabolism
Ataxia Telangiectasia - blood
Ataxia Telangiectasia - immunology
Biological and medical sciences
Biomarkers - blood
C-Reactive Protein - metabolism
CD4-CD8 Ratio
Child
Child, Preschool
Chromosome fragility (bloom syndrome, ataxia telangiectasia, fanconi anemia, x-linked mental retardation...)
Cross-Sectional Studies
Disease Progression
Female
Follow-Up Studies
General aspects
Humans
Immunoassay
Interleukin-8 - blood
Male
Medical genetics
Medical sciences
Middle Aged
Pediatrics
Phenotype
Prognosis
Retrospective Studies
Young Adult
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Description
Summary:Serum interleukin (IL)-8 levels were measured in 50 patients with ataxia telangiectasia (A-T) and 22 without A-T. In a cross-sectional study, the geometric mean of IL-8 level was significantly higher in the patients with A-T ( P
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2009.12.007