Experimental Babesia microti Infections in Non-Splenectomized Macaca mulatta

Eight non-splenectomized Macaca mulatta were inoculated intravenously with strains of Babesia microti that originally were isolated from 2 human cases of babesiosis and then were maintained in hamsters in the laboratory. Patent infections developed in 7 animals with peak parasitemias of 496 to 3,906...

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Bibliographic Details
Published in:The Journal of parasitology 1979-02, Vol.65 (1), p.144-146
Main Authors: Ruebush, Trenton K., Collins, William E., Healy, George R., Warren, McWilson
Format: Article
Language:English
Subjects:
Animals
Babesia - pathogenicity
Babesiosis
Babesiosis - parasitology
Babesiosis - veterinary
Blood
Haplorhini
Humans
Infections
Inoculation
Macaca mulatta
Male
Monkey Diseases - parasitology
Parasitemia
Parasites
Parasitic diseases
Parasitism
Splenectomy
Tropical medicine
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Description
Summary:Eight non-splenectomized Macaca mulatta were inoculated intravenously with strains of Babesia microti that originally were isolated from 2 human cases of babesiosis and then were maintained in hamsters in the laboratory. Patent infections developed in 7 animals with peak parasitemias of 496 to 3,906 organisms/mm3 blood. Prepatent periods ranged from 15 to 46 days. Parasitemia persisted for at least 90 days in all animals and in one, organisms were still present 559 days after inoculation.
ISSN:0022-3395
1937-2345
DOI:10.2307/3280219