Trimethopim-sulfamethoxazole compared with benzathine penicillin for treatment of impetigo in Aboriginal children: a pilot randomised controlled trial

We conducted a pilot randomized controlled trial comparing trimethoprim-sulfamethoxazole to benzathine penicillin for treatment of impetigo in Aboriginal children. Treatment was successful in 7 of 7 children treated with trimethoprim-sulfamethoxazole and 5 of 6 treated with benzathine penicillin. Tr...

Full description

Saved in:
Bibliographic Details
Published in:Journal of paediatrics and child health 2010-03, Vol.46 (3), p.131-133
Main Authors: Tong, Steven Y C, Andrews, Ross M, Kearns, Therese, Gundjirryirr, Rosalyn, McDonald, Malcolm I, Currie, Bart J, Carapetis, Jonathan R
Format: Article
Language:English
Subjects:
Administration, Oral
Adolescent
Anti-Infective Agents - administration & dosage
Anti-Infective Agents - therapeutic use
Antibiotics
Bacterial infections
Child
Child, Preschool
Clinical trials
Comparative studies
Female
Humans
Impetigo - drug therapy
Impetigo - microbiology
Infant
Injections, Intramuscular
Male
Methicillin-Resistant Staphylococcus aureus
Native children & youth
Northern Territory
Penicillin G Benzathine - administration & dosage
Penicillin G Benzathine - therapeutic use
Pilot Projects
Skin diseases
Staphylococcus aureus
Streptococcus pyogenes
Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage
Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We conducted a pilot randomized controlled trial comparing trimethoprim-sulfamethoxazole to benzathine penicillin for treatment of impetigo in Aboriginal children. Treatment was successful in 7 of 7 children treated with trimethoprim-sulfamethoxazole and 5 of 6 treated with benzathine penicillin. Trimethoprim-sulfamethoxazole achieved microbiological clearance and healing of sores from which beta-hemolytic streptococci and community-associated methicillin-resistant Staphylococcus aureus were initially cultured.
ISSN:1034-4810
1440-1754
1440-1754
DOI:10.1111/j.1440-1754.2010.01697.x