Extramedullary Plasmacytoma of the Cavernous Sinus

We present the case of an 80-year-old male with an history of multiple myeloma (MM) stage I with extramedullary plasmacytoma of the neck, diagnosed 18 months before and in complete remission after radiation therapy and melphalan-prednisone therapy. He was admitted with signs and symptoms characteris...

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Bibliographic Details
Published in:Leukemia & lymphoma 2002, Vol.43 (8), p.1691-1693
Main Authors: Vande Broek, I., Stadnik, T., Meurs, A., Maes, J., Van Camp, B., Schots, R.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cavernous Sinus
Cavernous Sinus Syndrome
Extramedullary Plasmacytoma
Humans
Magnetic Resonance Imaging
Male
Multiple Myeloma
Plasmacytoma - diagnosis
Plasmacytoma - therapy
Tomography, X-Ray Computed
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Summary:We present the case of an 80-year-old male with an history of multiple myeloma (MM) stage I with extramedullary plasmacytoma of the neck, diagnosed 18 months before and in complete remission after radiation therapy and melphalan-prednisone therapy. He was admitted with signs and symptoms characteristic for cavernous sinus syndrome, including diplopia, exophthalmia, ptosis and orbital pain. Magnetic resonance imaging showed a mass lesion in the cavernous sinus, consistent with relapsing extramedullary plasmacytoma. The patient received palliative radiation therapy and high dose dexamethasone, but treatment failed and the patient died. This case represents one of the few reports of extramedullary plasmacytoma of the cavernous sinus. The development of a clinical presentation of cavernous sinus syndrome in a patient with a history of MM or extramedullary plasmacytoma should raise the suspicion of a plasmacytic involvement of the cavernous sinus.
ISSN:1042-8194
1029-2403
DOI:10.1080/1042819021000003054