Risk for Contrast Nephropathy in Patients Undergoing Coronarography

Among the causes of in‐hospital acute renal failure, contrast‐induced nephropathy ranks third in prevalence. Although it represents a condition of renal impairment with spontaneous recovery, contrast nephropathy should always be considered, because it prolongs hospitalization and it may become a sev...

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Bibliographic Details
Published in:Artificial organs 2010-06, Vol.34 (6), p.E193-E199
Main Authors: Manna, Gaetano La, Pancaldi, Leonardo Goffredo, Capecchi, Alessandro, Maska, Edlira, Comai, Giorgia, Cappuccilli, Maria L., Carretta, Elisa, Lombardi, Alessandro, Colì, Luigi, Stefoni, Sergio
Format: Article
Language:English
Subjects:
Acute renal failure
Aged
Aged, 80 and over
Cardiology
Continuous venovenous hemofiltration
Contrast media
Contrast Media - adverse effects
Contrast media-induced nephropathy
Coronarography
Coronary Angiography - adverse effects
Female
Humans
Kidney Diseases - chemically induced
Kidney Diseases - epidemiology
Male
Periprocedural hydration
Risk Factors
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Summary:Among the causes of in‐hospital acute renal failure, contrast‐induced nephropathy ranks third in prevalence. Although it represents a condition of renal impairment with spontaneous recovery, contrast nephropathy should always be considered, because it prolongs hospitalization and it may become a severe complication requiring dialysis. The purposes of this study are: (i) to determine if the application of the most effective contrast‐induced nephropathy prevention strategies in the Cardiology Intensive Care Unit can prove to be successful in reducing nephropathy risk; and (ii) to identify which of the involved risk factors persist after the preventive treatment. We examined the patients who had a coronarography at the Bentivoglio hospital from April 2007 to April 2008 who required at least 3 days of permanence in hospital due to the presence of potential risk factors; 136 out of 784 patients were included. Among the selected patients, 21 (15.44%) developed a renal impairment compatible with contrast‐induced nephropathy. The risk factors that seemed to display the best correlation with risk of contrast nephropathy were advanced age and an ventricular failure (ejection fraction 70 years) determined a threefold increased risk of contrast nephropathy. Our data suggest that the development of contrast nephropathy following coronarography is associated with worse renal function during hospitalization and at discharge.
ISSN:0160-564X
1525-1594
DOI:10.1111/j.1525-1594.2009.00984.x