Are Working Memory Deficits in Bipolar Disorder Markers for Psychosis?

Working memory deficits have been identified in bipolar disorder, but there is evidence suggesting that these deficits may be markers for psychosis rather than affective disorder. The current study examined this issue by comparing two groups of individuals with bipolar disorder, one with psychotic f...

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Bibliographic Details
Published in:Neuropsychology 2010-03, Vol.24 (2), p.244-254
Main Authors: Allen, Daniel N, Randall, Carol, Bello, Danielle, Armstrong, Christina, Frantom, Linda, Cross, Chad, Kinney, Jefferson
Format: Article
Language:English
Subjects:
Acoustic Stimulation - methods
Adult
Adult and adolescent clinical studies
Biological and medical sciences
Bipolar Disorder
Bipolar Disorder - complications
Bipolar Disorder - diagnosis
Bipolar disorders
Diagnostic and Statistical Manual of Mental Disorders
Endophenotype
Executive Function
Female
Hospitalization - statistics & numerical data
Human
Humans
Male
Medical sciences
Memory Disorders - etiology
Memory, Short-Term - physiology
Middle Aged
Mood disorders
Neurocognition
Neuropsychological Tests
Phenotypes
Principal Component Analysis
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychosis
Psychotic Disorders - complications
Psychotic Disorders - diagnosis
Short Term Memory
Statistics as Topic
Young Adult
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Summary:Working memory deficits have been identified in bipolar disorder, but there is evidence suggesting that these deficits may be markers for psychosis rather than affective disorder. The current study examined this issue by comparing two groups of individuals with bipolar disorder, one with psychotic features and one without psychotic features, with a group of normal controls. Working memory was conceptualized as a multicomponent system that includes auditory and visuospatial short-term stores, executive control processes, and an episodic buffer that allows for communication between short- and long-term memory stores ( Baddeley & Logie, 1999 ). Results indicated that only executive control processes significantly differentiated the psychotic and nonpsychotic bipolar groups, although visuospatial working memory differentiated both bipolar groups from controls. The results support the idea that some aspects of working memory performance are markers for psychosis, while others may be more general markers for bipolar disorders.
ISSN:0894-4105
1931-1559
DOI:10.1037/a0018159