Antibiotic resistance of Stenotrophomonas maltophilia strains isolated from captive snakes

The minimum inhibitory concentrations (MICs) of 24 antibiotics were determined for 45 Stenotrophomonas maltophilia strains by the microdilution method at 37 and 30 °C (after 24 h and 48 h of incubation). The isolates were obtained from mouth swabs and pus of 116 captive snakes whereas the identical...

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Bibliographic Details
Published in:Folia microbiologica 2010, Vol.55 (1), p.83-87
Main Authors: Hejnar, P., Kolář, M., Sauer, P.
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - pharmacology
Antibiotic resistance
Antibiotics
Applied Microbiology
Biomedical and Life Sciences
Carrier State - microbiology
Carrier State - veterinary
Drug resistance
Drug Resistance, Bacterial
Environmental Engineering/Biotechnology
Gram-Negative Bacterial Infections - microbiology
Gram-Negative Bacterial Infections - veterinary
Immunology
Infections
Life Sciences
Microbial Sensitivity Tests
Microbiology
Mouth - microbiology
Snakes
Snakes - microbiology
Stenotrophomonas maltophilia
Stenotrophomonas maltophilia - drug effects
Stenotrophomonas maltophilia - isolation & purification
Suppuration - microbiology
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Summary:The minimum inhibitory concentrations (MICs) of 24 antibiotics were determined for 45 Stenotrophomonas maltophilia strains by the microdilution method at 37 and 30 °C (after 24 h and 48 h of incubation). The isolates were obtained from mouth swabs and pus of 116 captive snakes whereas the identical strains (based on PFGE) of the same origin were discarded. At 37 °C, the isolates showed a low frequency of resistance to levofloxacin (0 and 8.9 % of resistant strains after 24 and 48 h, MICs 50 0.5 and 1 mg/L, MICs 90 1 and 2 mg/L) and cotrimoxazole (2.2 % of resistant strains for 24 and 48 h, MICs 50 4 mg/L for both time periods, MICs 90 4 and 8). At 30 °C, the most effective drugs were also cotrimoxazole (2.2 and 6.7 %, MICs 50 4 and 8, MICs 90 8 and 32) and levofloxacin (8.9 and 46.7 %, MICs 50 1 and 2, MICs 90 2 and 4). The isolates were either identically or more susceptible to antibiotics than strains acquired from patients hospitalized at Olomouc University Hospital (the same region) with the exception of ciprofloxacin, cefoperazone, cefoperazone/sulbactam and ceftazidime.
ISSN:0015-5632
1874-9356
DOI:10.1007/s12223-010-0014-9