Multiple ulcers in primary syphilis with negative rapid plasma reagin and Venereal Disease Research Laboratory tests: an unusual presentation during the re-emergence of syphilis in Albania

Since 1995 infectious syphilis has re-emerged in Albania. As syphilis has become more common, more unusual presentations are being recognized. We present a case of an HIV-negative man with primary syphilis presenting with multiple penile ulcers and negative rapid plasma reagin and Venereal Disease R...

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Bibliographic Details
Published in:International journal of STD & AIDS 2010-03, Vol.21 (3), p.211-212
Main Authors: Harxhi, A, Kraja, D, Shehu, E, French, P
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Albania
Bacterial diseases
Bacterial diseases of the genital system
Biological and medical sciences
Communicable Diseases, Emerging - pathology
Early Diagnosis
Epidemiology. Vaccinations
False Negative Reactions
General aspects
Hemagglutination Tests
Human bacterial diseases
Human immunodeficiency virus
Humans
Infectious diseases
Male
Medical sciences
Penile Diseases - pathology
Reagins - blood
Skin Ulcer - microbiology
Skin Ulcer - pathology
Syphilis Serodiagnosis
Syphilis, Cutaneous - pathology
Treponema pallidum
Treponema pallidum - isolation & purification
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Summary:Since 1995 infectious syphilis has re-emerged in Albania. As syphilis has become more common, more unusual presentations are being recognized. We present a case of an HIV-negative man with primary syphilis presenting with multiple penile ulcers and negative rapid plasma reagin and Venereal Disease Research Laboratory tests. The case illustrates the challenges of diagnosing early syphilis and the importance of not relying on non-treponemal tests.
ISSN:0956-4624
1758-1052
DOI:10.1258/ijsa.2009.008463