Synthesis and antibacterial activity of some new derivatives of pyrazole

In this study, we report the synthesis and antibacterial activity of a new series of 5-amido-1-(2,4-dinitrophenyl)-1H-4-pyrazolecarbonitriles. Our results show that all compounds exhibit antimicrobial activities against methicillin susceptible Staphylococcus aureus and methicillin resistant S. aureu...

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Bibliographic Details
Published in:World journal of microbiology & biotechnology 2010-02, Vol.26 (2), p.317-321
Main Authors: Rahimizadeh, Mohammad, Pordel, Mehdi, Bakavoli, Mehdi, Rezaeian, Shima, Sadeghian, Ali
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial agents
Applied Microbiology
Bacteria
Biochemistry
Biological and medical sciences
Biomedical and Life Sciences
Biotechnology
Drug resistance
Environmental Engineering/Biotechnology
Ethanol
Fundamental and applied biological sciences. Psychology
Laboratories
Life Sciences
Microbiology
Original Paper
Staphylococcus aureus
Staphylococcus infections
Studies
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Summary:In this study, we report the synthesis and antibacterial activity of a new series of 5-amido-1-(2,4-dinitrophenyl)-1H-4-pyrazolecarbonitriles. Our results show that all compounds exhibit antimicrobial activities against methicillin susceptible Staphylococcus aureus and methicillin resistant S. aureus with MIC values of 25.1 and 91.0 μM.
ISSN:0959-3993
1573-0972
DOI:10.1007/s11274-009-0178-0