Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS)

Objective: Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS) that measures aspects of ADHD in adults. Method: Psychometric properties of the AISRS total and AISRS subscales are analyzed and compared to the Conners’ Adult Attention-Deficit/Hyperactivity Disorder Rating Scale-Inve...

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Bibliographic Details
Published in:Journal of attention disorders 2010-07, Vol.14 (1), p.57-68
Main Authors: Spencer, Thomas J., Adler, Lenard A., Meihua Qiao, Saylor, Keith E., Brown, Thomas E., Holdnack, James A., Schuh, Kory J., Trzepacz, Paula T., Kelsey, Douglas K.
Format: Article
Language:English
Subjects:
Adolescent
Adrenergic Uptake Inhibitors - therapeutic use
Adult
Adults
Atomoxetine Hydrochloride
Attention - physiology
Attention Deficit Disorder with Hyperactivity - diagnosis
Attention Deficit Disorder with Hyperactivity - drug therapy
Attention Deficit Hyperactivity Disorder
Correlation
Drug Therapy
Factor Analysis
Factor Analysis, Statistical
Humans
Impulsive Behavior - diagnosis
Middle Aged
Patients
Propylamines - therapeutic use
Psychiatric Status Rating Scales
Rating Scales
Reliability
Reproducibility of Results
Severity of Illness Index
Symptoms (Individual Disorders)
Treatment Outcome
Validity
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Summary:Objective: Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS) that measures aspects of ADHD in adults. Method: Psychometric properties of the AISRS total and AISRS subscales are analyzed and compared to the Conners’ Adult Attention-Deficit/Hyperactivity Disorder Rating Scale-Investigator Rated: Screening Version (CAARS-Inv:SV) and the Clinical Global Impression-ADHD-Severity Scale using data from a placebo-controlled 6-month clinical trial of once-daily atomoxetine. Results: The AISRS has high internal consistency, good convergent, and discriminant validities; modest divergent validity; and small ceiling and floor effects (≤1%). It correlates highly with the CAARS-Inv:SV. Factor analysis confirms 2 AISRS subscales, hyperactivity-impulsive scale and inattention. The AISRS total and AISRS subscales perform stably. All scales demonstrate responsiveness to change with medication. Conclusion: The AISRS and its subscales are robust, valid efficacy measures of ADHD symptoms in adult patients. Its anchored items and semistructured interview are advancements over existing scales. (J. of Att. Dis. 2010; 14(1) 57-68)
ISSN:1087-0547
1557-1246
DOI:10.1177/1087054709347435