Antibody response of rainbow trout with single or double infections involving viral haemorrhagic septicaemia virus and infectious haematopoietic necrosis virus

Juvenile rainbow trout Oncorhynchus mykiss were experimentally infected by immersion with viral haemorrhagic septicaemia virus (VHSV), infectious haematopoietic necrosis virus (IHNV) or with both viruses. The presence of neutralizing antibodies in the sera of infected fish were analysed by 50% plaqu...

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Bibliographic Details
Published in:Diseases of aquatic organisms 2009-01, Vol.83 (1), p.23-29
Main Authors: FREGENEDA-GRANDES, J. M, SKALL, H. F, OLESEN, N. J
Format: Article
Language:English
Subjects:
Agnatha. Pisces
Animal and plant ecology
Animal viral diseases
Animal, plant and microbial ecology
Animals
Antibodies, Viral - blood
Antibodies, Viral - immunology
Autoecology
Biological and medical sciences
Brackish
Fish Diseases - immunology
Fish Diseases - mortality
Fish Diseases - virology
Freshwater
Fundamental and applied biological sciences. Psychology
Infectious diseases
Infectious haematopoietic necrosis virus
Infectious hematopoietic necrosis virus - immunology
Marine
Medical sciences
Novirhabdovirus - immunology
Oncorhynchus mykiss
Rhabdoviridae Infections - immunology
Rhabdoviridae Infections - mortality
Rhabdoviridae Infections - veterinary
Rhabdoviridae Infections - virology
Vertebrata
Viral diseases
Viral hemorrhagic septicemia virus
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Summary:Juvenile rainbow trout Oncorhynchus mykiss were experimentally infected by immersion with viral haemorrhagic septicaemia virus (VHSV), infectious haematopoietic necrosis virus (IHNV) or with both viruses. The presence of neutralizing antibodies in the sera of infected fish were analysed by 50% plaque neutralization tests (50%PNT). In Group 1 (infected with VHSV) and Group 2 (infected with IHNV) neutralizing antibodies were found in 41% and 21% of the serum samples, respectively. No cross-reacting antibodies were found in these 2 groups. In Group 3 (infected with both viruses) 30% of the samples showed neutralizing antibodies against VHSV, 21% against IHNV and 12% against both viruses. Fish in Group 3 developed a double specific antibody reaction whose kinetics and intensity (mean of log10 titres) were similar to the antibody response of the single infected groups.
ISSN:0177-5103
1616-1580
DOI:10.3354/dao01993