Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves

• Published in: Food and chemical toxicology 2010-05, Vol.48 (5), p.1316-1320
• Main Authors: Moosavian, Hamid R., Mohri, Mehrdad, Seifi, Hesam A.
• Format: Article
• Language: English
• Subjects: Animals; Animals, Newborn; biochemistry; Biological and medical sciences; Blood Cells - drug effects; Blood Proteins - metabolism; Calves; Cattle; Chemical and industrial products toxicology. Toxic occupational diseases; dairy cattle; dietary minerals; Dietary Supplements; Drug Therapy, Combination; Ferric Compounds - pharmacology; Health; Hematinics - pharmacology; Hematologic Tests; Hematology; Iron; Iron - blood; Iron-Binding Proteins - metabolism; Medical sciences; Metals and various inorganic compounds; neonatal dairy calves; neonates; parenteral feeding; Toxicology; Vitamin A; Vitamin A - pharmacology; Weight gain; Weight Gain - drug effects
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/j.fct.2010.02.030

Forty Holstein calves were used for the experiment and randomly assigned to four different treatments. Treatments consisted of control (injections of 5 ml normal saline), test 1 (500 mg Fe injected to each calf at 24–48 h of age), test 2 (200,000 IU vitamin A was injected to each calf at 24–48 h of age), and test 3 (Fe and vitamin A were injected to each calf as mentioned previously. Group had significant effect on the amounts of HCT, RBC, hemoglobin, MCH, platelets, iron concentration and total iron binding capacity (TIBC) saturation ( p