Loading…

Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves

Forty Holstein calves were used for the experiment and randomly assigned to four different treatments. Treatments consisted of control (injections of 5 ml normal saline), test 1 (500 mg Fe injected to each calf at 24–48 h of age), test 2 (200,000 IU vitamin A was injected to each calf at 24–48 h of...

Full description

Saved in:
Bibliographic Details
Published in:Food and chemical toxicology 2010-05, Vol.48 (5), p.1316-1320
Main Authors: Moosavian, Hamid R., Mohri, Mehrdad, Seifi, Hesam A.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3
cites cdi_FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3
container_end_page 1320
container_issue 5
container_start_page 1316
container_title Food and chemical toxicology
container_volume 48
creator Moosavian, Hamid R.
Mohri, Mehrdad
Seifi, Hesam A.
description Forty Holstein calves were used for the experiment and randomly assigned to four different treatments. Treatments consisted of control (injections of 5 ml normal saline), test 1 (500 mg Fe injected to each calf at 24–48 h of age), test 2 (200,000 IU vitamin A was injected to each calf at 24–48 h of age), and test 3 (Fe and vitamin A were injected to each calf as mentioned previously. Group had significant effect on the amounts of HCT, RBC, hemoglobin, MCH, platelets, iron concentration and total iron binding capacity (TIBC) saturation ( p
doi_str_mv 10.1016/j.fct.2010.02.030
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_746295918</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0278691510001316</els_id><sourcerecordid>746295918</sourcerecordid><originalsourceid>FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3</originalsourceid><addsrcrecordid>eNqFkk2P0zAQhiMEYsvCD-ACuSAum-KPxE61p9Vq-ZBW4gB7tibOuHWVxsV2i_o7-MNMSIEbnKx59cw7o3ldFC85W3LG1bvt0tm8FIxqJpZMskfFgrdaVko2_HGxYEK3lVrx5qJ4ltKWMaa5Vk-LC2ppW93yRfHjzjm0OZXBlXuIOGaMMJThiLFKh_1-wB1pkH0YJ-ToM-z8WN6UMPalj5M6lhvcQQ5DWJ-uZq3zwZLoU44kfUe_3uRyDX68-tW3QRjyZvIbMYyQaWAPPp5KC8MR0_PiiYMh4Yvze1k8vL_7evuxuv_84dPtzX1la9nmSoKzTSOYkyCwU-hcLxVoJ5yytgOkygotO5K6VjWuFitRK81Yy5TuOMrL4u3su4_h2wFTNrSxxWEAWuuQjK6VWDUr3v6flFJJpeqGSD6TNoaUIjqzj34H8WQ4M1NoZmsoNDOFZpgwFBr1vDq7H7od9n86fqdEwJszAIlO5CKM1qe_nFDtqmbT8Ncz5yAYWEdiHr6QiySjWrNaEHE9E0h3PXqMJlmPo8XeR_oGpg_-H4v-BJC_v_g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733636645</pqid></control><display><type>article</type><title>Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves</title><source>ScienceDirect Freedom Collection</source><creator>Moosavian, Hamid R. ; Mohri, Mehrdad ; Seifi, Hesam A.</creator><creatorcontrib>Moosavian, Hamid R. ; Mohri, Mehrdad ; Seifi, Hesam A.</creatorcontrib><description>Forty Holstein calves were used for the experiment and randomly assigned to four different treatments. Treatments consisted of control (injections of 5 ml normal saline), test 1 (500 mg Fe injected to each calf at 24–48 h of age), test 2 (200,000 IU vitamin A was injected to each calf at 24–48 h of age), and test 3 (Fe and vitamin A were injected to each calf as mentioned previously. Group had significant effect on the amounts of HCT, RBC, hemoglobin, MCH, platelets, iron concentration and total iron binding capacity (TIBC) saturation ( p&lt;0.05). These parameters were significantly higher in test1 for RBC parameters, test 1 and test 3 for iron concentration and test 1 for TIBC saturation in comparing to control group. Age (sampling time) had significant effects on the values of most measured parameters ( p &lt; 0.05) except MCHC, WBC, TIBC, and TIBC saturation. Significant interactions between sampling time and group were seen for HCT, RBC number, hemoglobin concentration, and MCV. No significant differences were seen for total weight gain, and mean daily weight gain between groups. Chi-square test revealed no significant difference for the percent of days of treatment between trial groups.</description><identifier>ISSN: 0278-6915</identifier><identifier>EISSN: 1873-6351</identifier><identifier>DOI: 10.1016/j.fct.2010.02.030</identifier><identifier>PMID: 20188781</identifier><identifier>CODEN: FCTOD7</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Animals ; Animals, Newborn ; biochemistry ; Biological and medical sciences ; Blood Cells - drug effects ; Blood Proteins - metabolism ; Calves ; Cattle ; Chemical and industrial products toxicology. Toxic occupational diseases ; dairy cattle ; dietary minerals ; Dietary Supplements ; Drug Therapy, Combination ; Ferric Compounds - pharmacology ; Health ; Hematinics - pharmacology ; Hematologic Tests ; Hematology ; Iron ; Iron - blood ; Iron-Binding Proteins - metabolism ; Medical sciences ; Metals and various inorganic compounds ; neonatal dairy calves ; neonates ; parenteral feeding ; Toxicology ; Vitamin A ; Vitamin A - pharmacology ; Weight gain ; Weight Gain - drug effects</subject><ispartof>Food and chemical toxicology, 2010-05, Vol.48 (5), p.1316-1320</ispartof><rights>2010 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright (c) 2010 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3</citedby><cites>FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=22689405$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20188781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moosavian, Hamid R.</creatorcontrib><creatorcontrib>Mohri, Mehrdad</creatorcontrib><creatorcontrib>Seifi, Hesam A.</creatorcontrib><title>Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves</title><title>Food and chemical toxicology</title><addtitle>Food Chem Toxicol</addtitle><description>Forty Holstein calves were used for the experiment and randomly assigned to four different treatments. Treatments consisted of control (injections of 5 ml normal saline), test 1 (500 mg Fe injected to each calf at 24–48 h of age), test 2 (200,000 IU vitamin A was injected to each calf at 24–48 h of age), and test 3 (Fe and vitamin A were injected to each calf as mentioned previously. Group had significant effect on the amounts of HCT, RBC, hemoglobin, MCH, platelets, iron concentration and total iron binding capacity (TIBC) saturation ( p&lt;0.05). These parameters were significantly higher in test1 for RBC parameters, test 1 and test 3 for iron concentration and test 1 for TIBC saturation in comparing to control group. Age (sampling time) had significant effects on the values of most measured parameters ( p &lt; 0.05) except MCHC, WBC, TIBC, and TIBC saturation. Significant interactions between sampling time and group were seen for HCT, RBC number, hemoglobin concentration, and MCV. No significant differences were seen for total weight gain, and mean daily weight gain between groups. Chi-square test revealed no significant difference for the percent of days of treatment between trial groups.</description><subject>Animals</subject><subject>Animals, Newborn</subject><subject>biochemistry</subject><subject>Biological and medical sciences</subject><subject>Blood Cells - drug effects</subject><subject>Blood Proteins - metabolism</subject><subject>Calves</subject><subject>Cattle</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>dairy cattle</subject><subject>dietary minerals</subject><subject>Dietary Supplements</subject><subject>Drug Therapy, Combination</subject><subject>Ferric Compounds - pharmacology</subject><subject>Health</subject><subject>Hematinics - pharmacology</subject><subject>Hematologic Tests</subject><subject>Hematology</subject><subject>Iron</subject><subject>Iron - blood</subject><subject>Iron-Binding Proteins - metabolism</subject><subject>Medical sciences</subject><subject>Metals and various inorganic compounds</subject><subject>neonatal dairy calves</subject><subject>neonates</subject><subject>parenteral feeding</subject><subject>Toxicology</subject><subject>Vitamin A</subject><subject>Vitamin A - pharmacology</subject><subject>Weight gain</subject><subject>Weight Gain - drug effects</subject><issn>0278-6915</issn><issn>1873-6351</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqFkk2P0zAQhiMEYsvCD-ACuSAum-KPxE61p9Vq-ZBW4gB7tibOuHWVxsV2i_o7-MNMSIEbnKx59cw7o3ldFC85W3LG1bvt0tm8FIxqJpZMskfFgrdaVko2_HGxYEK3lVrx5qJ4ltKWMaa5Vk-LC2ppW93yRfHjzjm0OZXBlXuIOGaMMJThiLFKh_1-wB1pkH0YJ-ToM-z8WN6UMPalj5M6lhvcQQ5DWJ-uZq3zwZLoU44kfUe_3uRyDX68-tW3QRjyZvIbMYyQaWAPPp5KC8MR0_PiiYMh4Yvze1k8vL_7evuxuv_84dPtzX1la9nmSoKzTSOYkyCwU-hcLxVoJ5yytgOkygotO5K6VjWuFitRK81Yy5TuOMrL4u3su4_h2wFTNrSxxWEAWuuQjK6VWDUr3v6flFJJpeqGSD6TNoaUIjqzj34H8WQ4M1NoZmsoNDOFZpgwFBr1vDq7H7od9n86fqdEwJszAIlO5CKM1qe_nFDtqmbT8Ncz5yAYWEdiHr6QiySjWrNaEHE9E0h3PXqMJlmPo8XeR_oGpg_-H4v-BJC_v_g</recordid><startdate>20100501</startdate><enddate>20100501</enddate><creator>Moosavian, Hamid R.</creator><creator>Mohri, Mehrdad</creator><creator>Seifi, Hesam A.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20100501</creationdate><title>Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves</title><author>Moosavian, Hamid R. ; Mohri, Mehrdad ; Seifi, Hesam A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Animals</topic><topic>Animals, Newborn</topic><topic>biochemistry</topic><topic>Biological and medical sciences</topic><topic>Blood Cells - drug effects</topic><topic>Blood Proteins - metabolism</topic><topic>Calves</topic><topic>Cattle</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>dairy cattle</topic><topic>dietary minerals</topic><topic>Dietary Supplements</topic><topic>Drug Therapy, Combination</topic><topic>Ferric Compounds - pharmacology</topic><topic>Health</topic><topic>Hematinics - pharmacology</topic><topic>Hematologic Tests</topic><topic>Hematology</topic><topic>Iron</topic><topic>Iron - blood</topic><topic>Iron-Binding Proteins - metabolism</topic><topic>Medical sciences</topic><topic>Metals and various inorganic compounds</topic><topic>neonatal dairy calves</topic><topic>neonates</topic><topic>parenteral feeding</topic><topic>Toxicology</topic><topic>Vitamin A</topic><topic>Vitamin A - pharmacology</topic><topic>Weight gain</topic><topic>Weight Gain - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moosavian, Hamid R.</creatorcontrib><creatorcontrib>Mohri, Mehrdad</creatorcontrib><creatorcontrib>Seifi, Hesam A.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Food and chemical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moosavian, Hamid R.</au><au>Mohri, Mehrdad</au><au>Seifi, Hesam A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves</atitle><jtitle>Food and chemical toxicology</jtitle><addtitle>Food Chem Toxicol</addtitle><date>2010-05-01</date><risdate>2010</risdate><volume>48</volume><issue>5</issue><spage>1316</spage><epage>1320</epage><pages>1316-1320</pages><issn>0278-6915</issn><eissn>1873-6351</eissn><coden>FCTOD7</coden><abstract>Forty Holstein calves were used for the experiment and randomly assigned to four different treatments. Treatments consisted of control (injections of 5 ml normal saline), test 1 (500 mg Fe injected to each calf at 24–48 h of age), test 2 (200,000 IU vitamin A was injected to each calf at 24–48 h of age), and test 3 (Fe and vitamin A were injected to each calf as mentioned previously. Group had significant effect on the amounts of HCT, RBC, hemoglobin, MCH, platelets, iron concentration and total iron binding capacity (TIBC) saturation ( p&lt;0.05). These parameters were significantly higher in test1 for RBC parameters, test 1 and test 3 for iron concentration and test 1 for TIBC saturation in comparing to control group. Age (sampling time) had significant effects on the values of most measured parameters ( p &lt; 0.05) except MCHC, WBC, TIBC, and TIBC saturation. Significant interactions between sampling time and group were seen for HCT, RBC number, hemoglobin concentration, and MCV. No significant differences were seen for total weight gain, and mean daily weight gain between groups. Chi-square test revealed no significant difference for the percent of days of treatment between trial groups.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>20188781</pmid><doi>10.1016/j.fct.2010.02.030</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0278-6915
ispartof Food and chemical toxicology, 2010-05, Vol.48 (5), p.1316-1320
issn 0278-6915
1873-6351
language eng
recordid cdi_proquest_miscellaneous_746295918
source ScienceDirect Freedom Collection
subjects Animals
Animals, Newborn
biochemistry
Biological and medical sciences
Blood Cells - drug effects
Blood Proteins - metabolism
Calves
Cattle
Chemical and industrial products toxicology. Toxic occupational diseases
dairy cattle
dietary minerals
Dietary Supplements
Drug Therapy, Combination
Ferric Compounds - pharmacology
Health
Hematinics - pharmacology
Hematologic Tests
Hematology
Iron
Iron - blood
Iron-Binding Proteins - metabolism
Medical sciences
Metals and various inorganic compounds
neonatal dairy calves
neonates
parenteral feeding
Toxicology
Vitamin A
Vitamin A - pharmacology
Weight gain
Weight Gain - drug effects
title Effects of parenteral over-supplementation of vitamin A and iron on hematology, iron biochemistry, weight gain, and health of neonatal dairy calves
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T12%3A38%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20parenteral%20over-supplementation%20of%20vitamin%20A%20and%20iron%20on%20hematology,%20iron%20biochemistry,%20weight%20gain,%20and%20health%20of%20neonatal%20dairy%20calves&rft.jtitle=Food%20and%20chemical%20toxicology&rft.au=Moosavian,%20Hamid%20R.&rft.date=2010-05-01&rft.volume=48&rft.issue=5&rft.spage=1316&rft.epage=1320&rft.pages=1316-1320&rft.issn=0278-6915&rft.eissn=1873-6351&rft.coden=FCTOD7&rft_id=info:doi/10.1016/j.fct.2010.02.030&rft_dat=%3Cproquest_cross%3E746295918%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c438t-3afc5520f3a2eb6effd36a7f2f6ccbaed36c273ba7fb865f4292467008067b1e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=733636645&rft_id=info:pmid/20188781&rfr_iscdi=true