Carcinoma arising in the wall of congenital bile duct cysts

The incidence of carcinoma arising in the wall of the congenital bile duct cysts is much higher than previously assumed. The authors report 4 such cases of primary and secondary carcinomas and review their clinical features through the similar 59 cases in the literature. Of the 63 cases, the average...

Full description

Saved in:
Bibliographic Details
Published in:Cancer 1979-09, Vol.44 (3), p.1134-1141
Main Authors: Todani, Takuji, Tabuchi, Katsusuke, Watanabe, Yasuhiro, Kobayashi, Toshiyuki
Format: Article
Language:English
Subjects:
Adenocarcinoma - etiology
Adolescent
Adult
Aged
Carcinoma, Squamous Cell - etiology
Child
Child, Preschool
Common Bile Duct Diseases - complications
Common Bile Duct Diseases - congenital
Common Bile Duct Diseases - pathology
Common Bile Duct Neoplasms - etiology
Common Bile Duct Neoplasms - pathology
Cysts - complications
Cysts - congenital
Cysts - pathology
Digestive System Neoplasms - etiology
Drainage - adverse effects
Female
Humans
Male
Middle Aged
Risk
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The incidence of carcinoma arising in the wall of the congenital bile duct cysts is much higher than previously assumed. The authors report 4 such cases of primary and secondary carcinomas and review their clinical features through the similar 59 cases in the literature. Of the 63 cases, the average age was much younger, at least several decades, compared with cases of extrahepatic carcinoma without bile duct cysts. The female‐male ratio was 2.5:1. Racial preponderance was also observed, namely, the majority were Japanese. Additionally, many patients previously received various internal drainage procedures, especially choledochocystoduodenostomy. As the treatment, primary excision of the extrahepatic bile duct cyst seems to give the best results because it can avoid ascending cholangitis and prevent development of carcinoma. However, carcinoma still can arise in the intrahepatic bile duct cyst, which cannot be removed at the present time.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197909)44:3<1134::AID-CNCR2820440350>3.0.CO;2-T