Solubilities of the α II - and β-Forms of Synthetic Polypeptides: Evidence for an α II -β Transformation in the Amorphous Phase

IN previous communications 1,2 from these Laboratories, it has been shown that the molecular chains of a number of synthetic polypeptides can exist in folded and extended configurations, and the X-ray and infra-red evidence which has accumulated so far is entirely consistent with the view that the f...

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Published in:Nature (London) 1950-11, Vol.166 (4228), p.829-830
Main Authors: BAMFORD, C. H, HANBY, W. E, HAPPEY, F
Format: Article
Language:English
Subjects:
Humanities and Social Sciences
Humans
letter
multidisciplinary
Old Medline
Peptides
Science
Science (multidisciplinary)
Solubility
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description IN previous communications 1,2 from these Laboratories, it has been shown that the molecular chains of a number of synthetic polypeptides can exist in folded and extended configurations, and the X-ray and infra-red evidence which has accumulated so far is entirely consistent with the view that the folded form has the α II -structure proposed by Ambrose and Hanby 3 . One purpose of this note is to bring forward evidence of a different kind which has a bearing on the structure of the molecular fold.
doi_str_mv 10.1038/166829b0
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subjects Humanities and Social Sciences
Humans
letter
multidisciplinary
Old Medline
Peptides
Science
Science (multidisciplinary)
Solubility
title Solubilities of the α II - and β-Forms of Synthetic Polypeptides: Evidence for an α II -β Transformation in the Amorphous Phase
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