Different phenotypes of the group-specific component (Gc) in chimpanzees

The group-specific component (Gc) was examined in a sample of 78 chimpanzees (Pan troglodytes). With isoelectric focusing followed by immunofixation, two different phenotypes are observed. They both differ from the Gc types observed in man. Two alleles are postulated, one coding for a double-band co...

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Bibliographic Details
Published in:Human genetics 1979-01, Vol.50 (2), p.217-220
Main Authors: Cleve, H, Patutschnick, W
Format: Article
Language:English
Subjects:
Alleles
Animals
Calcium-Binding Proteins - genetics
Electrophoresis, Polyacrylamide Gel
Gene Frequency
Genetic Markers
Isoelectric Focusing
Pan troglodytes - genetics
Phenotype
S100 Calcium Binding Protein G - genetics
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Summary:The group-specific component (Gc) was examined in a sample of 78 chimpanzees (Pan troglodytes). With isoelectric focusing followed by immunofixation, two different phenotypes are observed. They both differ from the Gc types observed in man. Two alleles are postulated, one coding for a double-band component, the other coding for a single-band component. Neuraminidase experiments indicate the presence of sialic acid in the anodal component of the double-band pattern.
ISSN:0340-6717
1432-1203
DOI:10.1007/BF00390244