Microcirculation and blood volume in rats before and after spinal cord injury

Blood flow, cardiac output, blood pressure, indicator mixing time and blood volume were measured in rats before and after spinal cord injury. After cutting off the spinal cord blood flow decreases markedly in the paraplegic area but also in the main organs of the animals. Only the blood supply of th...

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Bibliographic Details
Published in:Paraplegia 1979-11, Vol.17 (4), p.436-440
Main Authors: Seifert, J, Lob, G, Probst, J, Brendel, W
Format: Article
Language:English
Subjects:
Animals
Blood Pressure
Blood Volume
Cardiac Output
Microcirculation - physiopathology
Paraplegia - physiopathology
Pulmonary Circulation
Rats
Spinal Cord Injuries - physiopathology
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Summary:Blood flow, cardiac output, blood pressure, indicator mixing time and blood volume were measured in rats before and after spinal cord injury. After cutting off the spinal cord blood flow decreases markedly in the paraplegic area but also in the main organs of the animals. Only the blood supply of the lung increases by this manipulation. As blood volume and the blood pressure is decreased and the indicator mixing time delayed the situation of the spinal cord injury can be compared with the situation after acute blood loss. Therefore it is proposed to include circulatory disturbances into the conception of the acute spinal shock situation.
ISSN:0031-1758
1362-4393
1476-5624
DOI:10.1038/sc.1979.85