Physiological evaluation of chronic right ventricular bypass

Abstract only Investigations with an implantable left ventricular (LV) assist pump indicated inadequate circulatory support in the presence of induced ventricular fibrillation (VF). Consequently, a right ventricular (RV) bypass pump was developed to provide a stable pulmonary blood flow. This report...

Full description

Saved in:
Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1971-05, Vol.43 (5 Suppl), p.I90-I95
Main Authors: LaFarge, C G, Bankole, M, Bernhard, W F
Format: Article
Language:English
Subjects:
Angiography
Animals
Assisted Circulation - instrumentation
Blood Cell Count
Blood Platelets
Cardiac Catheterization
Cattle
Hematocrit
Hemodynamics
Hemoglobins - analysis
Hemolysis
Lung Compliance
Time Factors
Ventricular Fibrillation - therapy
Ventricular Function
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract only Investigations with an implantable left ventricular (LV) assist pump indicated inadequate circulatory support in the presence of induced ventricular fibrillation (VF). Consequently, a right ventricular (RV) bypass pump was developed to provide a stable pulmonary blood flow. This report evaluates the physiological effects of the RV pump alone and in conjunction with an LV pump. Eleven calves have been evaluated by standard cardiac catheterization techniques during chronic pumping (1 to 85 days, mean 30 days, and continuing). Pressures, flows, and RV and LV function were monitored with transducer-tipped catheters and angiography. Effective pulmonary compliance was also measured. The RV bypass studies revealed (1) pump capability up to 8 L/min, reducing RV pressure and work to zero, (2) pulmonary artery pressure not significantly increased (20 to 40 mm Hg), (3) pulmonary compliance identical with sham-operated calves, and (4) no pathological changes noted in lungs. Data suggest that biventricular bypass pumps will provide chronic circulatory support during VF or biventricular failure.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.cir.43.5s1.i-90