Quality of life and adherence to HAART in HIV-infected patients

A review on adherence to highly active antiretroviral therapy and the quality of life of patients living with HIV in the scientific literature, indexed in MEDLINE between 1998 and 2008, was performed. Studies published in Portuguese, Spanish or English with patients over 18 years of age were include...

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Bibliographic Details
Published in:Revista de saúde pública 2010-08, Vol.44 (4), p.743-749
Main Authors: Geocze, Luciana, Mucci, Samantha, De Marco, Mario Alfredo, Nogueira-Martins, Luiz Antonio, Citero, Vanessa de Albuquerque
Format: Article
Language:eng ; por
Subjects:
Adult
Antiretroviral Therapy, Highly Active
HIV Infections - drug therapy
Humans
Medication Adherence - psychology
Medication Adherence - statistics & numerical data
Quality of Life
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Summary:A review on adherence to highly active antiretroviral therapy and the quality of life of patients living with HIV in the scientific literature, indexed in MEDLINE between 1998 and 2008, was performed. Studies published in Portuguese, Spanish or English with patients over 18 years of age were included. Reviews, case reports and letters were excluded. Of the 21 studies found, 12 were included (three clinical trials, three prospective cohorts and six cross-sectional studies). The relationship between quality of life and treatment adherence remains controversial, despite descriptive studies indicating the possibility of a positive association. The results may have been influenced by the specific characteristics of the described clinical trials and do not show a consensus regarding the impact of treatment adherence on patients' quality of life.
ISSN:1518-8787
DOI:10.1590/S0034-89102010000400019