Value of transvaginal ultrasound in assessing severity of pelvic endometriosis

• Published in: Ultrasound in obstetrics & gynecology 2010-08, Vol.36 (2), p.241-248
• Main Authors: Holland, T. K., Yazbek, J., Cutner, A., Saridogan, E., Hoo, W. L., Jurkovic, D.
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Classification; diagnosis; Digestive system. Abdomen; Endometriosis; Endometriosis - diagnostic imaging; Endoscopy; Female; Female genital diseases; Gynecology; Gynecology. Andrology. Obstetrics; Humans; Investigative techniques, diagnostic techniques (general aspects); Laparoscopy; Medical sciences; Middle Aged; Non tumoral diseases; Obstetrics; Pelvic Pain - diagnostic imaging; Pelvis; Preoperative Care; Prospective Studies; Scanning; Sensitivity and Specificity; severity; Severity of Illness Index; transvaginal ultrasound; Ultrasonography; Ultrasound; Vagina; Young Adult
• ISSN: 0960-7692; 1469-0705; 1469-0705
• DOI: 10.1002/uog.7689

Objective The objective of this study was to examine the ability of preoperative transvaginal ultrasound (TVS) scanning to assess the severity of pelvic endometriosis. Methods Consecutive women with clinically suspected or proven pelvic endometriosis, who were booked for laparoscopy, were invited to join the study. The severity of endometriosis was assessed preoperatively using TVS and the findings were compared with the results obtained by laparoscopy using the American Society for Reproductive Medicine (ASRM) classification. Results In total, 201 women had preoperative TVS and laparoscopies. Of these, no endometriosis was found at laparoscopy for 62/201 (30.8%; 95% CI, 24.8–37.5), whereas 33/201 (16.4%; 95% CI, 11.9–22.2) had minimal endometriosis, 31/201 (15.4%; 95% CI, 11.1–21.1) had mild endometriosis, 27/201 (13.4%; 95% CI, 9.4–18.8) had moderate endometriosis and 48/201 (23.9%; 95% CI, 18.5–30.2) had severe endometriosis. The sensitivity and specificity of the TVS diagnosis of severe pelvic endometriosis were 0.85 (95% CI, 0.716–0.934) and 0.98 (95% CI, 0.939–0.994), respectively, and the positive and negative likelihood ratios were 43.5 (95% CI, 14.1–134) and 0.15 (95% CI, 0.075–0.295), respectively. Overall, there was a good level of agreement between ultrasound and laparoscopy in identifying absent, minimal, mild, moderate and severe disease (quadratic weighted kappa = 0.786). The mean ASRM score difference between TVS and laparoscopy in assessing severity of endometriosis was − 2.398 (95% CI, − 4.685 to − 0.1112) and the limits of agreement were − 34.62 (95% CI, − 38.54 to − 30.709) to 29.83 (95% CI, 25.91–33.74). Conclusions TVS is a good test for assessing the severity of pelvic endometriosis. TVS is particularly accurate in detecting severe disease, which could facilitate more effective triaging of women for appropriate surgical care. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.