Comparison of inter‐ and intraobserver agreement and reliability between three different types of placental volume measurement technique (XI VOCAL™, VOCAL™ and multiplanar) and validity in the in‐vitro setting

• Published in: Ultrasound in obstetrics & gynecology 2010-08, Vol.36 (2), p.210-217
• Main Authors: Cheong, K. B., Leung, K. Y., Li, T. K. T., Chan, H. Y., Lee, Y. P., Tang, M. H. Y.
• Format: Article
• Language: English
• Subjects: 11–14 weeks' gestation; Biological and medical sciences; Female; Fetal Development; Fetuses; Gestation; Gestational Age; Gynecology; Gynecology. Andrology. Obstetrics; Humans; Image Processing, Computer-Assisted - instrumentation; Image Processing, Computer-Assisted - methods; imaging; Imaging, Three-Dimensional - instrumentation; Imaging, Three-Dimensional - methods; in vitro; Medical sciences; multiplanar; Observer Variation; Obstetrics; phantom; Phantoms, Imaging; Placenta; Placenta - anatomy & histology; Placenta - diagnostic imaging; Placenta - physiology; Pregnancy; Reproducibility of Results; Ultrasonography, Prenatal - instrumentation; Ultrasonography, Prenatal - methods; Ultrasound; validity; VOCAL; volume; XI VOCAL
• ISSN: 0960-7692; 1469-0705; 1469-0705
• DOI: 10.1002/uog.7609

Objectives To compare XI VOCAL™ (eXtended Imaging Virtual Organ Computer‐aided AnaLysis) for three‐dimensional (3D) ultrasound volumetry of the placenta and of phantom objects with a rotational method using VOCAL™ and with the multiplanar method. Methods We acquired 3D volume datasets from 32 fetuses at 11–14 weeks' gestation. Placental volume was calculated twice by each of two observers using XI VOCAL (with 5, 10, 15 and 20 slices), multiplanar (1‐mm interval) and VOCAL (with 12°, 18° and 30° rotation) methods. In addition, validity was assessed using the in‐vitro setting with three phantom objects of known volume. Results Both inter‐ and intraobserver reliabilities were very high for all three methods. There was no systematic bias between any two methods except between XI VOCAL (10 slices) and the multiplanar (1‐mm interval) method, with a smaller volume using the former method. The limits of agreement were wide between any two of the three methods. In the in‐vitro setting, there was a trend towards less valid measurements with the XI VOCAL technique and fewer slices. With the same number of steps, measurements made with VOCAL (12° and 18°) were more valid than were those made with XI VOCAL (15 and 10 slices, respectively). Conclusion XI VOCAL cannot be used interchangeably with VOCAL or multiplanar techniques in measuring placental volume at 11–14 weeks' gestation. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.