Epithelial pathways in choroid plexus electrolyte transport

A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transpor...

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Bibliographic Details
Published in:Physiology (Bethesda, Md.) Md.), 2010-08, Vol.25 (4), p.239-249
Main Authors: Damkier, Helle H, Brown, Peter D, Praetorius, Jeppe
Format: Article
Language:English
Subjects:
Animals
Bicarbonates - metabolism
Carrier Proteins - metabolism
Cerebrospinal Fluid - secretion
Chloride Channels - metabolism
Choroid Plexus - anatomy & histology
Choroid Plexus - metabolism
Choroid Plexus - physiology
Epithelium - metabolism
Epithelium - physiology
Humans
Potassium Channels - metabolism
Sodium Channels - physiology
Water - metabolism
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Summary:A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transport of the electrolytes Na+, K+, Cl-, and HCO3(-)across the choroid plexus epithelium.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00011.2010