Effect of Traditional and Integrative Regimens on Quality of Life and Early Renal Impairment in Elderly Patients with Isolated Systolic Hypertension

Objective：To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension（EISH）.Methods： A multi-center,randomized,double-blinded controlled trail was adopted.A total of 270 cases o...

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Published in:Chinese journal of integrative medicine 2010-06, Vol.16 (3), p.216-221
Main Author: 李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰
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Language:English
Subjects:
Aged
Aged, 80 and over
Antihypertensive Agents - pharmacology
Antihypertensive Agents - therapeutic use
Blood Pressure - drug effects
Drugs, Chinese Herbal - pharmacology
Drugs, Chinese Herbal - therapeutic use
Female
Humans
Hypertension - drug therapy
Hypertension - physiopathology
Integrative Medicine
Kidney - drug effects
Kidney - pathology
Kidney - physiopathology
Male
Medicine
Medicine & Public Health
Original Article
Quality of Life
Systole - drug effects
Systole - physiology
作者
患者
收缩压
早期
治疗方案
生活质量
老年病
高血压
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creator 李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰
description Objective：To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension（EISH）.Methods： A multi-center,randomized,double-blinded controlled trail was adopted.A total of 270 cases of EISH were randomly divided into 3 groups：Chinese medicine group（CM）,combination group and Western medicine group （WM）.The course of treatment was 4 weeks.The clinical blood pressure,integral of quality of life（SF-36 scale）, immunoglubin G（IgG）,microalbumin（mALB）,β_2-microglobulin（β_2-MG）,transferrin（TRF）and N-acetyl-β＇- D-glucosa-minidase（NAG）in urine were determined before and after the treatment.Results：After treatment, systolic blood pressure depressed significantly in each group（P〈0.05）,and the combination group was superior to CM or WM group in depressing SBP（P〈0.05）; in each group,integral of quality of life improved in different degree,and combination group was superior to WM group in all 8 dimensions（P〈0.05）.The level of mALB andβ_2-MG in urine decreased in all groups（P〈0.05）,and the combination group was superior to CM group or WM group in decreasing mALB（P〈0.05）.Conclusions：Chinese medical regimen has affirmative effect in treating EISH patients,and could lower the systolic blood pressure,improve quality of life and early renal impairment of the patients,and integrative medical regimen has superiority on account of cooperation,and deserves further study.
doi_str_mv 10.1007/s11655-010-0216-y
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in each group,integral of quality of life improved in different degree,and combination group was superior to WM group in all 8 dimensions（P〈0.05）.The level of mALB andβ_2-MG in urine decreased in all groups（P〈0.05）,and the combination group was superior to CM group or WM group in decreasing mALB（P〈0.05）.Conclusions：Chinese medical regimen has affirmative effect in treating EISH patients,and could lower the systolic blood pressure,improve quality of life and early renal impairment of the patients,and integrative medical regimen has superiority on account of cooperation,and deserves further study.</description><identifier>ISSN: 1672-0415</identifier><identifier>EISSN: 1993-0402</identifier><identifier>DOI: 10.1007/s11655-010-0216-y</identifier><identifier>PMID: 20694775</identifier><language>eng</language><publisher>Heidelberg: Chinese Association of Traditional and Western Medicine</publisher><subject>Aged ; Aged, 80 and over ; Antihypertensive Agents - pharmacology ; Antihypertensive Agents - therapeutic use ; Blood Pressure - drug effects ; Drugs, Chinese Herbal - pharmacology ; Drugs, Chinese Herbal - therapeutic use ; Female ; Humans ; Hypertension - drug therapy ; Hypertension - physiopathology ; Integrative Medicine ; Kidney - drug effects ; Kidney - pathology ; Kidney - physiopathology ; Male ; Medicine ; Medicine &amp; Public Health ; Original Article ; Quality of Life ; Systole - drug effects ; Systole - physiology ; 作者 ; 患者 ; 收缩压 ; 早期 ; 治疗方案 ; 生活质量 ; 老年病 ; 高血压</subject><ispartof>Chinese journal of integrative medicine, 2010-06, Vol.16 (3), p.216-221</ispartof><rights>Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-2e7d9a82c109bc2bb285be017b4aadb6fa68089fe577ca28d91298ce8fdda0543</citedby><cites>FETCH-LOGICAL-c370t-2e7d9a82c109bc2bb285be017b4aadb6fa68089fe577ca28d91298ce8fdda0543</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86437A/86437A.jpg</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20694775$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰</creatorcontrib><title>Effect of Traditional and Integrative Regimens on Quality of Life and Early Renal Impairment in Elderly Patients with Isolated Systolic Hypertension</title><title>Chinese journal of integrative medicine</title><addtitle>Chin. J. Integr. Med</addtitle><addtitle>Chinese Journal of Integrative Medicine</addtitle><description>Objective：To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension（EISH）.Methods： A multi-center,randomized,double-blinded controlled trail was adopted.A total of 270 cases of EISH were randomly divided into 3 groups：Chinese medicine group（CM）,combination group and Western medicine group （WM）.The course of treatment was 4 weeks.The clinical blood pressure,integral of quality of life（SF-36 scale）, immunoglubin G（IgG）,microalbumin（mALB）,β_2-microglobulin（β_2-MG）,transferrin（TRF）and N-acetyl-β＇- D-glucosa-minidase（NAG）in urine were determined before and after the treatment.Results：After treatment, systolic blood pressure depressed significantly in each group（P〈0.05）,and the combination group was superior to CM or WM group in depressing SBP（P〈0.05）; in each group,integral of quality of life improved in different degree,and combination group was superior to WM group in all 8 dimensions（P〈0.05）.The level of mALB andβ_2-MG in urine decreased in all groups（P〈0.05）,and the combination group was superior to CM group or WM group in decreasing mALB（P〈0.05）.Conclusions：Chinese medical regimen has affirmative effect in treating EISH patients,and could lower the systolic blood pressure,improve quality of life and early renal impairment of the patients,and integrative medical regimen has superiority on account of cooperation,and deserves further study.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antihypertensive Agents - pharmacology</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Blood Pressure - drug effects</subject><subject>Drugs, Chinese Herbal - pharmacology</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - physiopathology</subject><subject>Integrative Medicine</subject><subject>Kidney - drug effects</subject><subject>Kidney - pathology</subject><subject>Kidney - physiopathology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Original Article</subject><subject>Quality of Life</subject><subject>Systole - drug effects</subject><subject>Systole - physiology</subject><subject>作者</subject><subject>患者</subject><subject>收缩压</subject><subject>早期</subject><subject>治疗方案</subject><subject>生活质量</subject><subject>老年病</subject><subject>高血压</subject><issn>1672-0415</issn><issn>1993-0402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNp9kc9u1DAQxiMEoqXwAFyQxYVTwHbi2DmiaktXWol_5Ww59njr4sRb2ynKe_DAddiFIyePPL_vm9F8VfWa4PcEY_4hEdIxVmOCa0xJVy9PqnPS902NW0yflrrjtNSEnVUvUrrDmPEOs-fVGcVd33LOzqvfG2tBZxQsuonKuOzCpDxSk0HbKcM-quweAH2DvRthSihM6OusvMvLKtk5C3_YjYp-KdSq3Y4H5WKhM3IT2ngDa-9LMSpfCf1y-RZtU_Aqg0Hfl5SDdxpdLweIuYwoC7ysnlnlE7w6vRfVj6vNzeV1vfv8aXv5cVfrhuNcU-CmV4JqgvtB02Gggg2ACR9apczQWdUJLHoLjHOtqDA9ob3QIKwxCrO2uajeHX0PMdzPkLIcXdLgvZogzEnyVvRMNKIpJDmSOoaUIlh5iG5UcZEEyzULecxClizkmoVciubNyX0eRjD_FH-PXwB6BFJpTXuI8i7MsZww_df17WmT2zDt74tODkr_tM6DbFrMGoJp8wixIaNW</recordid><startdate>20100601</startdate><enddate>20100601</enddate><creator>李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰</creator><general>Chinese Association of Traditional and Western Medicine</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W95</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100601</creationdate><title>Effect of Traditional and Integrative Regimens on Quality of Life and Early Renal Impairment in Elderly Patients with Isolated Systolic Hypertension</title><author>李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-2e7d9a82c109bc2bb285be017b4aadb6fa68089fe577ca28d91298ce8fdda0543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antihypertensive Agents - pharmacology</topic><topic>Antihypertensive Agents - therapeutic use</topic><topic>Blood Pressure - drug effects</topic><topic>Drugs, Chinese Herbal - pharmacology</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension - drug therapy</topic><topic>Hypertension - physiopathology</topic><topic>Integrative Medicine</topic><topic>Kidney - drug effects</topic><topic>Kidney - pathology</topic><topic>Kidney - physiopathology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Original Article</topic><topic>Quality of Life</topic><topic>Systole - drug effects</topic><topic>Systole - physiology</topic><topic>作者</topic><topic>患者</topic><topic>收缩压</topic><topic>早期</topic><topic>治疗方案</topic><topic>生活质量</topic><topic>老年病</topic><topic>高血压</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库-农业科学</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chinese journal of integrative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>李浩 刘龙涛 赵文明 刘剑刚 姚明江 韩永祥 沈雁朋 刘兴东 刘丽 王雪梅 蔡琳琳 官杰</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Traditional and Integrative Regimens on Quality of Life and Early Renal Impairment in Elderly Patients with Isolated Systolic Hypertension</atitle><jtitle>Chinese journal of integrative medicine</jtitle><stitle>Chin. J. Integr. Med</stitle><addtitle>Chinese Journal of Integrative Medicine</addtitle><date>2010-06-01</date><risdate>2010</risdate><volume>16</volume><issue>3</issue><spage>216</spage><epage>221</epage><pages>216-221</pages><issn>1672-0415</issn><eissn>1993-0402</eissn><abstract>Objective：To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension（EISH）.Methods： A multi-center,randomized,double-blinded controlled trail was adopted.A total of 270 cases of EISH were randomly divided into 3 groups：Chinese medicine group（CM）,combination group and Western medicine group （WM）.The course of treatment was 4 weeks.The clinical blood pressure,integral of quality of life（SF-36 scale）, immunoglubin G（IgG）,microalbumin（mALB）,β_2-microglobulin（β_2-MG）,transferrin（TRF）and N-acetyl-β＇- D-glucosa-minidase（NAG）in urine were determined before and after the treatment.Results：After treatment, systolic blood pressure depressed significantly in each group（P〈0.05）,and the combination group was superior to CM or WM group in depressing SBP（P〈0.05）; in each group,integral of quality of life improved in different degree,and combination group was superior to WM group in all 8 dimensions（P〈0.05）.The level of mALB andβ_2-MG in urine decreased in all groups（P〈0.05）,and the combination group was superior to CM group or WM group in decreasing mALB（P〈0.05）.Conclusions：Chinese medical regimen has affirmative effect in treating EISH patients,and could lower the systolic blood pressure,improve quality of life and early renal impairment of the patients,and integrative medical regimen has superiority on account of cooperation,and deserves further study.</abstract><cop>Heidelberg</cop><pub>Chinese Association of Traditional and Western Medicine</pub><pmid>20694775</pmid><doi>10.1007/s11655-010-0216-y</doi><tpages>6</tpages></addata></record>
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1993-0402
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subjects Aged
Aged, 80 and over
Antihypertensive Agents - pharmacology
Antihypertensive Agents - therapeutic use
Blood Pressure - drug effects
Drugs, Chinese Herbal - pharmacology
Drugs, Chinese Herbal - therapeutic use
Female
Humans
Hypertension - drug therapy
Hypertension - physiopathology
Integrative Medicine
Kidney - drug effects
Kidney - pathology
Kidney - physiopathology
Male
Medicine
Medicine & Public Health
Original Article
Quality of Life
Systole - drug effects
Systole - physiology
作者
患者
收缩压
早期
治疗方案
生活质量
老年病
高血压
title Effect of Traditional and Integrative Regimens on Quality of Life and Early Renal Impairment in Elderly Patients with Isolated Systolic Hypertension
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