Prognostic Value of Normal Stress Myocardial Perfusion Imaging and Ventricular Function in Japanese Asymptomatic Patients With Type 2 Diabetes: A Study Based on the J-ACCESS-2 Database

Background: This study was designed to determine the clinical risk for hard events after normal single-photon emission computed tomography (SPECT) and to identify the predictors of increased risk in asymptomatic patients with diabetes mellitus, based on a Japanese Assessment of Cardiac Events and Su...

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Published in:Circulation Journal 2010, Vol.74(9), pp.1916-1921
Main Authors: Matsuo, Shinro, Nakajima, Kenichi, Yamasaki, Yoshimitsu, Kashiwagi, Atsunori, Nishimura, Tsunehiko
Format: Article
Language:English
Subjects:
Asian Continental Ancestry Group
Cardiovascular Diseases - diagnosis
Coronary Angiography - adverse effects
Diabetes Mellitus, Type 2 - physiopathology
Diagnostic Techniques, Cardiovascular
Female
Humans
Male
Organophosphorus Compounds
Organotechnetium Compounds
Prognosis
Radionuclide imaging
SPECT
Tomography, Emission-Computed, Single-Photon - adverse effects
Tomography, Emission-Computed, Single-Photon - methods
Tomography, Emission-Computed, Single-Photon - standards
Ventricular Function
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Summary:Background: This study was designed to determine the clinical risk for hard events after normal single-photon emission computed tomography (SPECT) and to identify the predictors of increased risk in asymptomatic patients with diabetes mellitus, based on a Japanese Assessment of Cardiac Events and Survival Studies by quantitative gated SPECT (J-ACCESS)-2 study. Methods and Results: A total of 513 consecutive asymptomatic patients who underwent stress 99mTc-tetrofosmin SPECT in Japan were included in this study. Based on SPECT image and QGS data, 319 had a summed stress score ≤3, a summed difference score
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-10-0098