Clinical Predictors of Culprit Plaque Rupture Assessed on Intravascular Ultrasound in Acute Coronary Syndrome

Background: Acute coronary syndrome (ACS) commonly results from vulnerable plaque rupture, and occasionally results from thrombus formation in lesions without plaque rupture. The aim of the present study was to clarify the clinical features of different etiology of ACS and clinical predictors of cul...

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Bibliographic Details
Published in:Circulation Journal 2010, Vol.74(9), pp.1936-1942
Main Authors: Kato, Masaya, Dote, Keigo, Naganuma, Toru, Sasaki, Shota, Ueda, Kentaro, Okita, Misa, Watanabe, Yoshikazu, Kajikawa, Masato, Yokoyama, Haruko, Higashi, Akifumi
Format: Article
Language:English
Subjects:
Acute coronary syndrome
Acute Coronary Syndrome - diagnostic imaging
Acute Coronary Syndrome - pathology
Age Factors
Aged
Atherosclerosis - diagnosis
Cholesterol, HDL - blood
Coronary Artery Disease - diagnosis
Female
Humans
Intravascular ultrasound
Male
Metabolic Syndrome
Middle Aged
Obesity
Plaque rupture
Predictive Value of Tests
Risk Factors
Rupture, Spontaneous - diagnosis
Sex Factors
Ultrasonography, Interventional
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Summary:Background: Acute coronary syndrome (ACS) commonly results from vulnerable plaque rupture, and occasionally results from thrombus formation in lesions without plaque rupture. The aim of the present study was to clarify the clinical features of different etiology of ACS and clinical predictors of culprit plaque rupture assessed on intravascular ultrasound (IVUS). Methods and Results: One hundred and ten ACS patients with emergent coronary angiography were classified into 2 groups based on the presence or absence of culprit plaque rupture assessed on IVUS. Clinical characteristics were compared between the 2 groups. Culprit coronary plaque rupture was observed in 60 patients (55%). Patients with plaque rupture were younger and were more likely to be male (P
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-10-0086