Relapsing infiltrates after pneumocystis pneumonia in stem cell transplant patients: think about BOOP

Bronchiolitis Obliterans Organizing Pneumonia (BOOP) can complicate allogeneic haematopoietic stem cell transplantation. It is associated with prior graft-versus-host disease (GVHD) and the case fatality is 21%. In 22%, diagnosis is preceded by tapering the corticosteroids given as a treatment for G...

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Bibliographic Details
Published in:Acta clinica belgica (English ed. Online) 2010-05, Vol.65 (3), p.200-201
Main Authors: Deeren, D, Lammertijn, L, Van Dorpe, J
Format: Article
Language:English
Subjects:
Aged
Bacterial pneumonia
Care and treatment
Complications and side effects
Corticosteroids
Cryptogenic Organizing Pneumonia - diagnosis
Cryptogenic Organizing Pneumonia - etiology
Cryptogenic Organizing Pneumonia - therapy
Glucocorticoids - administration & dosage
Glucocorticoids - adverse effects
Hematopoietic Stem Cell Transplantation - adverse effects
Hematopoietic stem cells
Humans
Male
Methylprednisolone - administration & dosage
Methylprednisolone - adverse effects
Pneumocystis carinii
Pneumonia
Pneumonia, Pneumocystis - complications
Pneumonia, Pneumocystis - drug therapy
Pneumonia, Pneumocystis - pathology
Stem cells
Transplantation
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Summary:Bronchiolitis Obliterans Organizing Pneumonia (BOOP) can complicate allogeneic haematopoietic stem cell transplantation. It is associated with prior graft-versus-host disease (GVHD) and the case fatality is 21%. In 22%, diagnosis is preceded by tapering the corticosteroids given as a treatment for GVHD. We report a fatal case of BOOP after tapering the corticosteroids that the patient received for a Pneumocystis jirovecii pneumonia after stem cell transplantation.
ISSN:1784-3286
2295-3337
DOI:10.1179/acb.2010.042