Colon carcinoma in childhood

Two cases of colon carcinoma in children without a family history of polyposis or gastrointestinal malignancy are reported. Details of the post-surgical treatment with 5-fluorouracil are stated, along with a brief recounting of the literature which served as a basis for the therapeutic approach util...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1971-08, Vol.48 (2), p.307-312
Main Authors: Donaldson, M H, Taylor, P, Rawitscher, R, Sewell, Jr, J B
Format: Article
Language:English
Subjects:
Adenocarcinoma, Mucinous - diagnosis
Adenocarcinoma, Mucinous - diagnostic imaging
Adenocarcinoma, Mucinous - drug therapy
Adenocarcinoma, Mucinous - pathology
Adenocarcinoma, Mucinous - surgery
Adolescent
Age Factors
Barium Sulfate
Child
Colonic Neoplasms - diagnosis
Colonic Neoplasms - diagnostic imaging
Colonic Neoplasms - drug therapy
Colonic Neoplasms - pathology
Colonic Neoplasms - surgery
Female
Fluorouracil - therapeutic use
Humans
Male
Radiography
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Summary:Two cases of colon carcinoma in children without a family history of polyposis or gastrointestinal malignancy are reported. Details of the post-surgical treatment with 5-fluorouracil are stated, along with a brief recounting of the literature which served as a basis for the therapeutic approach utilized in these two patients. The tumor-free intervals of 14 and 20 months are impressive in view of the advanced stages of the lesions and, thus, suggest 5-FU should be utilized in children with colon cancer as it is in such adults.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.48.2.307