The value of myelography in the management of childhood medulloblastoma

Sixteen children with newly diagnosed medulloblastomas underwent myelography prior to radiotherapy. None had clinical evidence suggesting spinal cord involvement. Seven patients (43%) were discovered to have unsuspected metastases involving the cord. Cerebrospinal fluid (CSF) cytology results were i...

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Bibliographic Details
Published in:Cancer 1980-04, Vol.45 (8), p.2194-2197
Main Authors: Deutsch, Melvin, Reigel, Donald H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Brain Neoplasms - cerebrospinal fluid
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - radiotherapy
Child
Child, Preschool
Female
Humans
Male
Medulloblastoma - cerebrospinal fluid
Medulloblastoma - diagnostic imaging
Medulloblastoma - radiotherapy
Myelography - methods
Prognosis
Spinal Cord Neoplasms - diagnostic imaging
Spinal Cord Neoplasms - radiotherapy
Spinal Cord Neoplasms - secondary
Citations: Items that this one cites
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Summary:Sixteen children with newly diagnosed medulloblastomas underwent myelography prior to radiotherapy. None had clinical evidence suggesting spinal cord involvement. Seven patients (43%) were discovered to have unsuspected metastases involving the cord. Cerebrospinal fluid (CSF) cytology results were inaccurate in predicting spinal cord involvement. Additional radiation was administered to the demonstrated lesions. Thirteen children (81%) are alive and well 7–53 months (average 26) from completion of therapy. One of nine children with a normal myelogram initially, and two of seven with initial spinal cord involvement have relapsed.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19800415)45:8<2194::AID-CNCR2820450831>3.0.CO;2-M