Treatment experience: Locally advanced sarcomas with 15 MeV fast neutrons

Experience with ten evaluable osseous sarcomas and ten evaluable advanced soft tissue sarcomas treated with neutrons of a mean neutron energy of 15 MeV are described. Neutron irradiation with or without conventional megavoltage radiotherapy is an effective modality in the treatment of these patients...

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Bibliographic Details
Published in:Cancer 1980-06, Vol.45 (11), p.2712-2716
Main Authors: Ornitz, Robert, Herskovic, Arnold, Schell, Michael, Fender, Frances, Rogers, Charles C.
Format: Article
Language:English
Subjects:
Bone Neoplasms - pathology
Bone Neoplasms - radiotherapy
Evaluation Studies as Topic
Fast Neutrons - therapeutic use
Humans
Neoplasm Recurrence, Local
Neutrons - therapeutic use
Pilot Projects
Prognosis
Radiotherapy, High-Energy
Sarcoma - pathology
Sarcoma - radiotherapy
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - radiotherapy
Time Factors
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Summary:Experience with ten evaluable osseous sarcomas and ten evaluable advanced soft tissue sarcomas treated with neutrons of a mean neutron energy of 15 MeV are described. Neutron irradiation with or without conventional megavoltage radiotherapy is an effective modality in the treatment of these patients. No correlation between response rate and grade or whether fast neutrons alone or combined with megavoltage radiotherapy was noted. Those patients receiving a neutron dose of 2195 neutron plus gamma rads or greater all had a complete response.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19800601)45:11<2712::AID-CNCR2820451103>3.0.CO;2-H