Blastomycoma of the cerebellum. An ultrastructural study

Biopsy tissue from a cerebellar blastomycoma in a 48-year-old man was studied by electron microscopy. The fine structure of the fungi recapitulated that of the yeast forms described in cultures and culture implants. Mycelial forms were not encountered. The yeasts displayed lamellated cell walls and...

Full description

Saved in:
Bibliographic Details
Published in:Acta neuropathologica 1980, Vol.50 (2), p.109-114
Main Authors: Mirra, S S, Trombley, I K, Miles, M L
Format: Article
Language:English
Subjects:
Biopsy
Blastomycosis - pathology
Cell Membrane - ultrastructure
Cerebellar Diseases - pathology
Cerebellum - pathology
Cerebellum - ultrastructure
Desmosomes - ultrastructure
Humans
Macrophages - ultrastructure
Male
Microscopy, Electron
Middle Aged
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Biopsy tissue from a cerebellar blastomycoma in a 48-year-old man was studied by electron microscopy. The fine structure of the fungi recapitulated that of the yeast forms described in cultures and culture implants. Mycelial forms were not encountered. The yeasts displayed lamellated cell walls and occasional multinucleation. Persistent broad-based budding with complex membranous profiles related to the cell membrane was prominent. The organisms were found within multinucleated giant cells and macrophages which exhibited subplasmalemmal linear densities and occasional desmosomal junctions.
ISSN:0001-6322
1432-0533
DOI:10.1007/BF00692860