Non-Effect of Hyaluronidase on the Spread of Œstrone

SINCE it is known that hyaluronidase increases the spread of certain substances in the skin of mammals by increasing the permeability of the dermis 1 , it appeared possible that this enzyme might affect the spread of œstrone where this can be shown to be localized in the dermis.

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Bibliographic Details
Published in:Nature (London) 1953-01, Vol.171 (4340), p.46-47
Main Authors: BROMHEAD, MARY E, 'ESPINASSE, PAUL G
Format: Article
Language:English
Subjects:
Contraceptive Agents, Female
Estrogens - administration & dosage
Estrone
Female
Humanities and Social Sciences
Humans
Hyaluronoglucosaminidase - pharmacology
letter
multidisciplinary
Old Medline
Science
Science (multidisciplinary)
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Description
Summary:SINCE it is known that hyaluronidase increases the spread of certain substances in the skin of mammals by increasing the permeability of the dermis 1 , it appeared possible that this enzyme might affect the spread of œstrone where this can be shown to be localized in the dermis.
ISSN:0028-0836
1476-4687
DOI:10.1038/171046a0