Metabolic Studies on Cardiac Tissue Obtained by Needle Biopsy in the Intact Unanesthetized Dog

This paper describes the use of needle biopsy of the heart as a method of obtaining specimens of cardiac muscle for biochemical study in the intact Unanesthetized dog. The procedure is simple and may be repeated many times. Studies indicate that tissue obtained by this method resembles conventional...

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Bibliographic Details
Published in:Circulation research 1953-05, Vol.1 (3), p.226-229
Main Authors: Casten, Gus G, Marsh, Julian B
Format: Article
Language:English
Subjects:
Animals
Biopsy, Needle
Dogs
Heart
Myocardium - metabolism
Old Medline
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Summary:This paper describes the use of needle biopsy of the heart as a method of obtaining specimens of cardiac muscle for biochemical study in the intact Unanesthetized dog. The procedure is simple and may be repeated many times. Studies indicate that tissue obtained by this method resembles conventional heart slices in its behavior in vitro. Included are data on respiration and the effect of digitalis on cardiac glycogen stores.
ISSN:0009-7330
1524-4571
DOI:10.1161/01.RES.1.3.226