Phosphate reabsorption in juxtamedullary nephron terminal segments

Adult Munich Wistar rats undergoing mild salt diuresis (NaCl 20 g x l-1, 0.1 ml x min-1) were injected with tracer doses of 3H-Inulin and 32P-sodium phosphate in thin descending and ascending limbs of Henle's loop, collecting ducts accessible at the surface of the papilla and early distal super...

Full description

Saved in:
Bibliographic Details
Published in:Pflügers Archiv 1980-08, Vol.387 (1), p.27-31
Main Authors: Poujeol, P, Jamison, R L, de Rouffignac, C
Format: Article
Language:English
Subjects:
Animals
Female
Juxtaglomerular Apparatus - metabolism
Kidney Tubules, Collecting - metabolism
Kidney Tubules, Distal - metabolism
Kidney Tubules, Proximal - metabolism
Phosphates - metabolism
Rats
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Adult Munich Wistar rats undergoing mild salt diuresis (NaCl 20 g x l-1, 0.1 ml x min-1) were injected with tracer doses of 3H-Inulin and 32P-sodium phosphate in thin descending and ascending limbs of Henle's loop, collecting ducts accessible at the surface of the papilla and early distal superficial tubules. Kidneys were prepared for simultaneous papillar microinjection and urinary flow collection. Expressed in percent of the amounts injected, unidirectional phosphate reabsorption fluxes were 5 +/- 1% and 3 +/- 1% for injections into early distal superficial tubules and collecting ducts, respectively. By contrast, the flux was 21.7 +/- 3% for injections into either the descending or ascending thin limbs of juxtamedullary nephrons. We conclude from these results that in the rat, a significant amount of phosphate is reabsorbed by the juxtamedullary distal tubules and/or the subsequent arcades connecting the juxtamedullary distal tubules to the collecting ducts.
ISSN:0031-6768
1432-2013
DOI:10.1007/BF00580840