ON-LINE Po2 AND PN2o ANALYSIS WITH AN IN VIVO CATHETER ELECTRODE

A technique was developed for the in vivo determination of Po2 and PN2o with a catheter electrode using double-pulse polarography. The method was evaluated in dog studies comparing readings from the electrode with those from a mass spectrometer employing an in vivo probe. The oxygen readings obtaine...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1980-08, Vol.52 (8), p.715-722
Main Authors: BROOKS, W.N., HAHN, C.E.W., FOËX, P., MAYNARD, P., ALBERY, W.J.
Format: Article
Language:English
Subjects:
Animals
Blood Gas Analysis - methods
Catheterization
Dogs
Electrodes
Halothane - pharmacology
Mass Spectrometry
Nitrous Oxide - blood
Oxygen - blood
Partial Pressure
Polarography
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Summary:A technique was developed for the in vivo determination of Po2 and PN2o with a catheter electrode using double-pulse polarography. The method was evaluated in dog studies comparing readings from the electrode with those from a mass spectrometer employing an in vivo probe. The oxygen readings obtained from the catheter electrode were also compared with values obtained by conventional blood-gas analysis. Good agreement was observed between the electrode and the mass spectrometer for both Po2 and PN2o. Similar agreement was found between the electrode readings and blood-gas analysis for Po2. In the presence of halothane, the electrode over-read for both Po2 and PN2O; a remedy is suggested. The in vivo electrode provides an effective, less expensive, alternative to the mass spectrometer for the on-line measurement of Po2, and PN2o in vivo.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/52.8.715