Metabolic indices of pulmonary damage. Changes in angiotensin converting enzyme and alpha 1 anti-trypsin activity after cardiopulmonary bypass

The activity of angiotensin-converting enzyme was measured in patients undergoing cardiopulmonary bypass and in a control group requiring thoracotomy for pulmonary surgery. The activity of the enzyme was higher in patients with cardiac disease, fell during operations involving cardiopulmonary bypass...

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Bibliographic Details
Published in:Anaesthesia 1980-09, Vol.35 (9), p.863-867
Main Authors: Claremont, D J, Branthwaite, M A
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
alpha 1-Antitrypsin - blood
Cardiopulmonary Bypass
Coronary Artery Bypass
Female
Heart Valve Prosthesis
Humans
Intraoperative Period
Lung Diseases - surgery
Male
Middle Aged
Peptidyl-Dipeptidase A - blood
Postoperative Period
Time Factors
Citations: Items that this one cites
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Summary:The activity of angiotensin-converting enzyme was measured in patients undergoing cardiopulmonary bypass and in a control group requiring thoracotomy for pulmonary surgery. The activity of the enzyme was higher in patients with cardiac disease, fell during operations involving cardiopulmonary bypass, but did not change during thoracotomy for pulmonary surgery. Possible reasons for these differences are discussed. The activity of another enzyme, alpha 1 anti-trypsin, did not change during cardiopulmonary bypass and no arteriovenous difference could be detected during or after operation.
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.1980.tb03944.x