Agitation thrombolysis for fresh iatrogenic IVC thrombosis in patients with Budd-Chiari syndrome

• Published in: Journal of vascular surgery 2010-09, Vol.52 (3), p.782-784
• Main Authors: Ding, Peng-Xu, MD, Li, Yong-Dong, MD, PhD, Han, Xin-Wei, MD, PhD, Wu, Gang, MD
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Blood. Blood coagulation. Reticuloendothelial system; Budd-Chiari Syndrome - diagnosis; Budd-Chiari Syndrome - physiopathology; Budd-Chiari Syndrome - therapy; Catheterization - adverse effects; Female; Fibrinolytic Agents - administration & dosage; Humans; Iatrogenic Disease; Male; Medical sciences; Middle Aged; Pharmacology. Drug treatments; Phlebography; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Thrombolytic Therapy - methods; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vascular Patency; Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels; Vena Cava, Inferior - diagnostic imaging; Vena Cava, Inferior - physiopathology; Venous Thrombosis - diagnosis; Venous Thrombosis - drug therapy; Venous Thrombosis - etiology; Venous Thrombosis - physiopathology
• ISSN: 0741-5214; 1097-6809
• DOI: 10.1016/j.jvs.2010.02.016

Three patients with Budd-Chiari syndrome (BCS) and fresh inferior vena cava (IVC) thrombosis were treated by agitation thrombolysis as a mechanical thrombectomy procedure and followed up by duplex ultrasonography. Agitation thrombolysis was technically and clinically successful in all patients. Inferior vena cavagrams after the procedure showed complete resolution of the iatrogenic, fresh IVC thrombi without occurrence of pulmonary embolism. Duplex ultrasonography follow-ups after 12, 24, and 28 months, respectively, confirmed complete patency of the IVC without rethrombosis and reobstruction. The results indicate that agitation thrombolysis may be a safe and feasible approach for BCS patients with iatrogenic, fresh IVC thrombosis.