A highly adaptable catalyst/substrate system for the synthesis of substituted chromenes

The gold(I)-catalyzed endo-cyclization of o-(1-hydroxyallyl)phenols to form chromenes is reported. The title compounds are prepared in high yield from readily available substrates. The system tolerates both electron rich and deficient aryl rings and a high degree of substitution on the allyl moiety.

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (36), p.6849-6851
Main Authors: Aponick, Aaron, Biannic, Berenger, Jong, Michael R
Format: Article
Language:English
Subjects:
Aromatic compounds
Benzopyrans - chemical synthesis
Benzopyrans - chemistry
Catalysis
Catalysts
Coordination Complexes - chemistry
Cyclization
Gold - chemistry
Synthesis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The gold(I)-catalyzed endo-cyclization of o-(1-hydroxyallyl)phenols to form chromenes is reported. The title compounds are prepared in high yield from readily available substrates. The system tolerates both electron rich and deficient aryl rings and a high degree of substitution on the allyl moiety.
ISSN:1359-7345
1364-548X
DOI:10.1039/c0cc01961e