Effect of topical applications of heavy suspensions of killed Malassezia ovalis on rabbit skin

Heavy applications of suspensions of killed Malassezia ovalis on rabbit skin produced lesions that both grossly and microscopically resembled human psoriasis. This system may afford not only a model but also an explanation for that disease.

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Bibliographic Details
Published in:Mycopathologia (1975) 1980-01, Vol.72 (3), p.147-154
Main Authors: Rosenberg, E W, Belew, P, Bale, G
Format: Article
Language:English
Subjects:
Animals
Complement Pathway, Alternative
Disease Models, Animal
Female
Malassezia - immunology
Malassezia - pathogenicity
Neutrophils
Psoriasis - etiology
Psoriasis - pathology
Rabbits
Skin - pathology
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Description
Summary:Heavy applications of suspensions of killed Malassezia ovalis on rabbit skin produced lesions that both grossly and microscopically resembled human psoriasis. This system may afford not only a model but also an explanation for that disease.
ISSN:0301-486X
1573-0832
DOI:10.1007/bf00572657